Protein Alignment Sur-8 and Lrriq4

DIOPT Version :9

• Sequence 1: NP_001262665.1
• Gene: Sur-8 / 42093
• FlyBaseID: FBgn0038504
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: XP_011248011.1
• Gene: Lrriq4 / 68307
• MGIID: 1915557
• Length: 599
• Species: Mus musculus
• Alignment Length: 578
• Identity: 156/578 - (26%)
• Similarity: 251/578 - (43%)
• Gaps: 91/578 - (15%)

  Fly   118 ETRPKMVTVKHPESNKPKP-----TTKKSKPIQADQDVIKALQRCRDEGIKRLDLSKSSITVIPS 177
            |..||::..|.|.....:.     :.:..|.|.::...:|.|:        .:.|..:.|..||.
Mouse    48 EHLPKVLQKKEPHQLTDRTFFIDGSNQGLKTIPSEILALKELE--------EVHLENNQIAEIPQ 104

  Fly   178 TVKECVHLTELYLYSNKIGQLPPEIGCLVSLRNLALNEN------------------------SL 218
            .:::..:...|||::|.:..|.||:|.|.||.:|.|:.|                        .|
Mouse   105 GIQQLQNTKVLYLHNNSLQDLCPELGALSSLESLDLSGNPLVISSLHVVSRLRTLRELRLYRTGL 169

  Fly   219 TSLPESL-QNCSQLKVLDLRHNKLAEIPPVIYRLRSLTTLYLRFNRITAVADDLRQLVNLTMLSL 282
            |.:|..: ::...|::..|..|.|..:|..|.....|..:||:.|.......||..|.||.::.|
Mouse   170 TEIPTGICKSLHHLELFGLSENFLESLPEEIVNQTKLREIYLKQNHFEVFPCDLCVLYNLEVIDL 234

  Fly   283 RENKIRELGSAIGALVNLTTLDVSHNHLEHLPEDIGNCVNLSALDLQHNELLDIPDSIGNLKSLV 347
            .|||::.:...||.||.|....|:.|||..|||.:..|..||.|||.||.:..:|.|:..|..|.
Mouse   235 DENKLKSIPGDIGHLVRLQKFYVASNHLMSLPESLSQCSKLSVLDLTHNSIHSLPSSLELLTELT 299

  Fly   348 RLGMRYNRLSSVPATLKNCKSMDEFNVEGNGITQLPDGMLASLSGLTTITLSRNQFASYPTGGPA 412
            .:|:..|||..||..|.:..|:....:....:..|.|. ...|..|..:.||:|....:|....|
Mouse   300 EVGLSGNRLEKVPRLLCSWVSLHLLYLRNTSLHGLRDS-FKRLINLRFLDLSQNHIEHFPVQICA 363

  Fly   413 QFTNVYSINLEHNRIDKIPYGIFSRAKGLTKLNMKENMLTALPLDIGTWVNMVELNLAT---NAL 474
             ..|:..:.|:.|::.::|..| |....|..|.:..|.|.:.|.:|.:.:::.:|.:..   :.|
Mouse   364 -LKNLEILALDDNKVRQLPPSI-SLLSNLKILGLTGNDLLSFPEEIFSLISLEKLYIGQDQGSKL 426

  Fly   475 QKLPDDIMNLQNLEILILSNNMLKKIPNTIGNLRKLRILDLEENRIEVLPHEIGLLHELQRLILQ 539
            ..||::|..|.||:.|.:.||.|:::|.::|.:..|.:||...|.::.||..|.....|:.|:|:
Mouse   427 SSLPENIKRLMNLKELYIENNRLEQLPASLGLMPNLEVLDCRHNLLKQLPDAICRTRNLRELLLE 491

  Fly   540 TNQITMLPRSIGHLGNLTHLSVSENNLQFLPEEIGSLESLENLYINQNPGLEKLPFELALCQNLK 604
            .|.:..||.::.||.||..|::..|.:...|           :|: .|.|.|      |:.::||
Mouse   492 DNLLCCLPENLDHLVNLKVLTLMNNPMVDPP-----------IYV-CNQGNE------AIWKHLK 538

  Fly   605 YLNIDKCPLSTIPPEIQAGGPSLVLQWLKMHSPYRQMXDVDGVWRTVYVGSDCYYQYE 662
            ...|.|...:|    |||        |                ||.:.|... |..||
Mouse   539 ENRIRKMMATT----IQA--------W----------------WRGIMVRKG-YGSYE 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sur-8	NP_001262665.1	leucine-rich repeat	163..184	CDD:275380	4/20 (20%)
		leucine-rich repeat	185..207	CDD:275380	9/21 (43%)
		LRR_RI	204..401	CDD:238064	66/221 (30%)
		LRR_8	207..264	CDD:290566	18/81 (22%)
		leucine-rich repeat	208..230	CDD:275380	7/46 (15%)
		leucine-rich repeat	231..253	CDD:275380	6/21 (29%)
		LRR_8	252..310	CDD:290566	20/57 (35%)
		leucine-rich repeat	254..276	CDD:275380	7/21 (33%)
		leucine-rich repeat	277..299	CDD:275380	8/21 (38%)
		LRR_8	299..356	CDD:290566	22/56 (39%)
		leucine-rich repeat	300..322	CDD:275380	9/21 (43%)
		leucine-rich repeat	323..345	CDD:275380	10/21 (48%)
		LRR_8	344..403	CDD:290566	16/58 (28%)
		leucine-rich repeat	346..368	CDD:275380	8/21 (38%)
		leucine-rich repeat	369..392	CDD:275380	3/22 (14%)
		LRR_RI	<379..566	CDD:238064	54/189 (29%)
		leucine-rich repeat	417..440	CDD:275380	5/22 (23%)
		leucine-rich repeat	441..486	CDD:275380	12/47 (26%)
		LRR_8	463..520	CDD:290566	18/59 (31%)
		leucine-rich repeat	487..507	CDD:275380	7/19 (37%)
		leucine-rich repeat	510..532	CDD:275380	7/21 (33%)
		LRR_8	532..588	CDD:290566	14/55 (25%)
		leucine-rich repeat	556..578	CDD:275380	4/21 (19%)
		leucine-rich repeat	603..626	CDD:275380	8/22 (36%)
Lrriq4	XP_011248011.1	LRR_RI	48..309	CDD:393385	76/268 (28%)
		leucine-rich repeat	89..111	CDD:275380	5/29 (17%)
		leucine-rich repeat	112..135	CDD:275380	9/22 (41%)
		leucine-rich repeat	183..205	CDD:275380	6/21 (29%)
		leucine-rich repeat	206..228	CDD:275380	7/21 (33%)
		LRR	228..521	CDD:227223	92/295 (31%)
		leucine-rich repeat	229..251	CDD:275380	8/21 (38%)
		leucine-rich repeat	252..274	CDD:275380	9/21 (43%)
		leucine-rich repeat	275..297	CDD:275380	10/21 (48%)
		leucine-rich repeat	298..320	CDD:275380	8/21 (38%)
		leucine-rich repeat	321..343	CDD:275380	3/22 (14%)
		leucine-rich repeat	344..366	CDD:275380	6/22 (27%)
		leucine-rich repeat	367..389	CDD:275380	5/22 (23%)
		leucine-rich repeat	390..438	CDD:275380	12/47 (26%)
		leucine-rich repeat	413..436	CDD:275380	5/22 (23%)
		leucine-rich repeat	439..461	CDD:275380	7/21 (33%)
		leucine-rich repeat	462..484	CDD:275380	7/21 (33%)
		leucine-rich repeat	485..507	CDD:275380	8/21 (38%)
		IQ	543..563	CDD:197470	9/48 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	54	1.000	Domainoid score	I11246
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45752
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100