Protein Alignment Sur-8 and Lrrc57

DIOPT Version :9

• Sequence 1: NP_001262665.1
• Gene: Sur-8 / 42093
• FlyBaseID: FBgn0038504
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: NP_001153082.1
• Gene: Lrrc57 / 66606
• MGIID: 1913856
• Length: 281
• Species: Mus musculus
• Alignment Length: 266
• Identity: 73/266 - (27%)
• Similarity: 122/266 - (45%)
• Gaps: 74/266 - (27%)

  Fly   357 SSVPATLKNCKSMDEFNVEGNGITQLPDGMLASLSGLTTITLSRNQFASYPTGGPAQFTNVYSIN 421
            |::.|.::..:....|.::..|:|:.|    :.|..||                    :|:.:|:
Mouse    46 SALRAHVETAQKTGVFQLKDRGLTEFP----SELQKLT--------------------SNLRTID 86

  Fly   422 LEHNRIDKIPYGIFSRAKGLTKLNMKENMLTALPLDIGTWVNMVELNLATNALQKLPDDIMNLQN 486
            |.:|:||.:|                       ||.||.:..:..|:|..|.|..|||::.||:.
Mouse    87 LSNNKIDSLP-----------------------PLIIGKFTLLKSLSLNNNKLTVLPDELCNLKK 128

  Fly   487 LEILILSNNMLKKIPNTIGNLRKLRILDLEENRIEVLPHEIGLLHELQRLILQTNQITMLPRSIG 551
            ||.|.|:||.|:::|:|.|.|..|:.|.|..|::..||.::..|..|..:.|..|||    |||
Mouse   129 LETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQI----RSI- 188

  Fly   552 HLGNLTHLSVSENNLQFLPEEIGSLESLENLYINQNPGLEKLPFELALCQNLKYLNIDK-C-PLS 614
                              |:.:|.|:::| |.:|||. :.:|..:::.|..||.|.::: | .||
Mouse   189 ------------------PDTVGELQAIE-LNLNQNQ-ISQLSVKISCCPRLKVLRLEENCLELS 233

  Fly   615 TIPPEI 620
            .:|..|
Mouse   234 MLPQSI 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sur-8	NP_001262665.1	leucine-rich repeat	163..184	CDD:275380
		leucine-rich repeat	185..207	CDD:275380
		LRR_RI	204..401	CDD:238064	9/43 (21%)
		LRR_8	207..264	CDD:290566
		leucine-rich repeat	208..230	CDD:275380
		leucine-rich repeat	231..253	CDD:275380
		LRR_8	252..310	CDD:290566
		leucine-rich repeat	254..276	CDD:275380
		leucine-rich repeat	277..299	CDD:275380
		LRR_8	299..356	CDD:290566
		leucine-rich repeat	300..322	CDD:275380
		leucine-rich repeat	323..345	CDD:275380
		LRR_8	344..403	CDD:290566	9/45 (20%)
		leucine-rich repeat	346..368	CDD:275380	2/10 (20%)
		leucine-rich repeat	369..392	CDD:275380	5/22 (23%)
		LRR_RI	<379..566	CDD:238064	51/186 (27%)
		leucine-rich repeat	417..440	CDD:275380	6/22 (27%)
		leucine-rich repeat	441..486	CDD:275380	13/44 (30%)
		LRR_8	463..520	CDD:290566	24/56 (43%)
		leucine-rich repeat	487..507	CDD:275380	10/19 (53%)
		leucine-rich repeat	510..532	CDD:275380	7/21 (33%)
		LRR_8	532..588	CDD:290566	15/55 (27%)
		leucine-rich repeat	556..578	CDD:275380	3/21 (14%)
		leucine-rich repeat	603..626	CDD:275380	8/20 (40%)
Lrrc57	NP_001153082.1	LRR	<62..>211	CDD:227223	60/220 (27%)
		leucine-rich repeat	82..105	CDD:275380	10/45 (22%)
		leucine-rich repeat	106..128	CDD:275380	9/21 (43%)
		leucine-rich repeat	129..151	CDD:275380	11/21 (52%)
		leucine-rich repeat	152..174	CDD:275380	7/21 (33%)
		leucine-rich repeat	175..197	CDD:275380	11/44 (25%)
		leucine-rich repeat	198..219	CDD:275380	7/22 (32%)
		leucine-rich repeat	220..241	CDD:275380	8/20 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910