DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sur-8 and AT1G73066

DIOPT Version :9

Sequence 1:	NP_001262665.1	Gene:	Sur-8 / 42093	FlyBaseID:	FBgn0038504	Length:	694	Species:	Drosophila melanogaster
Sequence 2:	NP_001117591.1	Gene:	AT1G73066 / 6240885	AraportID:	AT1G73066	Length:	598	Species:	Arabidopsis thaliana

Alignment Length:	494	Identity:	144/494 - (29%)
Similarity:	231/494 - (46%)	Gaps:	91/494 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   165 LDLSKSSIT-VIPSTVKECVHLTELYLYSNKI-------------------------GQLPPEIG 203
            :|||::|.: .:|.|:.....|.:||||||.:                         |.:|..:|
plant   126 IDLSENSFSGKVPDTLGSLKSLADLYLYSNSLTGELPKSLFRIPVLNYLHVEHNNLTGLIPQNVG 190

  Fly   204 CLVSLRNLALNENSLT-SLPESLQNCSQLKVLDLRHNKL-AEIPPVIYRLRSLTTLYLRFNRITA 266
            ....|.:|.|.:|..| ::|||:.|||:|::|.|..||| ..:|..:..|.|||.|::..|
plant   191 EAKELLHLRLFDNQFTGTIPESIGNCSKLEILYLHKNKLVGSLPASLNLLESLTDLFVANN---- 251

  Fly   267 VADDLRQLVNLTMLSLRENKIRELGSAIGALVNLTTLDVSHNHLE-HLPEDIGNCVNLSALDLQH 330
               .||..|.......|               ||.|||:|:|..| .:|.::|||.:|.||.:..
plant   252 ---SLRGTVQFGSTKCR---------------NLVTLDLSYNEFEGGVPPELGNCSSLDALVIVS 298

  Fly   331 NELL-DIPDSIGNLKSLVRLGMRYNRLS-SVPATLKNCKSMDEFNVEGNGITQLPDGM---LASL 390
            ..|. .||.|:|.||:|..|.:..|||| |:||.|.||.|::...:..|   ||..|:   |..|
plant   299 GNLSGTIPSSLGMLKNLTILNLSENRLSGSIPAELGNCSSLNLLKLNDN---QLVGGIPSALGKL 360

  Fly   391 SGLTTITLSRNQFASYPTGGPAQFTNVYSINLEHNRIDKIPYGIFSRAKGLTKLNMKENMLTA-L 454
            ..|.::.|..|:|:.                       :||..|: :.:.||:|.:..|.||. |
plant   361 RKLESLELFENRFSG-----------------------EIPIEIW-KIQSLTQLLVYRNNLTGKL 401

  Fly   455 PLDIGTWVNMVELNLATNALQ-KLPDDIMNLQNLEIL-ILSNNMLKKIPNTIGNLRKLRILDLEE 517
            |.:|....|:..:.|..|:.. .:|.::....||||: .:.||...:||..:.:.:.|.:.:|..
plant   402 PEEITKLKNLKIVTLFNNSFYGVIPPNLGLNSNLEIIDFIGNNFTGEIPRNLCHGKMLTVFNLGS 466

  Fly   518 NRIE-VLPHEIGLLHELQRLILQTNQIT-MLPRSIGHLGNLTHLSVSENNLQF-LPEEIGSLESL 579
            ||:. .:|..:.....|.|.||:.|.:: .||: .....:|:.|.::.|:.:. :|..:||..:|
plant   467 NRLHGKIPASVSQCKTLSRFILRENNLSGFLPK-FSKNQDLSFLDLNSNSFEGPIPRSLGSCRNL 530

  Fly   580 ENLYINQNPGLEKLPFELALCQNLKYLNIDKCPLS-TIP 617
            ..:.:::|.....:|.||...|||.:||:....|: |:|
plant   531 TTINLSRNKLTRNIPRELENLQNLSHLNLGSNLLNGTVP 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sur-8	NP_001262665.1	leucine-rich repeat	163..184	CDD:275380	6/19 (32%)
		leucine-rich repeat	185..207	CDD:275380	10/46 (22%)
		LRR_RI	204..401	CDD:238064	71/204 (35%)
		LRR_8	207..264	CDD:290566	24/58 (41%)
		leucine-rich repeat	208..230	CDD:275380	10/22 (45%)
		leucine-rich repeat	231..253	CDD:275380	8/22 (36%)
		LRR_8	252..310	CDD:290566	16/57 (28%)
		leucine-rich repeat	254..276	CDD:275380	6/21 (29%)
		leucine-rich repeat	277..299	CDD:275380	1/21 (5%)
		LRR_8	299..356	CDD:290566	25/58 (43%)
		leucine-rich repeat	300..322	CDD:275380	11/22 (50%)
		leucine-rich repeat	323..345	CDD:275380	9/22 (41%)
		LRR_8	344..403	CDD:290566	23/62 (37%)
		leucine-rich repeat	346..368	CDD:275380	12/22 (55%)
		leucine-rich repeat	369..392	CDD:275380	6/25 (24%)
		LRR_RI	<379..566	CDD:238064	48/194 (25%)
		leucine-rich repeat	417..440	CDD:275380	3/22 (14%)
		leucine-rich repeat	441..486	CDD:275380	13/46 (28%)
		LRR_8	463..520	CDD:290566	15/58 (26%)
		leucine-rich repeat	487..507	CDD:275380	7/20 (35%)
		leucine-rich repeat	510..532	CDD:275380	5/22 (23%)
		LRR_8	532..588	CDD:290566	14/57 (25%)
		leucine-rich repeat	556..578	CDD:275380	6/22 (27%)
		leucine-rich repeat	603..626	CDD:275380	6/16 (38%)
AT1G73066	NP_001117591.1	LRRNT_2	27..70	CDD:285463
		leucine-rich repeat	75..98	CDD:275380
		LRR_8	97..157	CDD:290566	13/30 (43%)
		leucine-rich repeat	99..122	CDD:275380
		leucine-rich repeat	123..146	CDD:275380	6/19 (32%)
		leucine-rich repeat	147..170	CDD:275380	7/22 (32%)
		leucine-rich repeat	171..194	CDD:275380	3/22 (14%)
		leucine-rich repeat	195..218	CDD:275380	10/22 (45%)
		leucine-rich repeat	219..242	CDD:275380	8/22 (36%)
		leucine-rich repeat	243..266	CDD:275380	8/44 (18%)
		leucine-rich repeat	267..290	CDD:275380	11/22 (50%)
		LRR_8	289..349	CDD:290566	24/62 (39%)
		leucine-rich repeat	291..314	CDD:275380	9/22 (41%)
		leucine-rich repeat	315..336	CDD:275380	10/20 (50%)
		leucine-rich repeat	339..362	CDD:275380	6/25 (24%)
		LRR_RI	359..586	CDD:238064	60/236 (25%)
		leucine-rich repeat	363..386	CDD:275380	7/46 (15%)
		leucine-rich repeat	387..410	CDD:275380	9/22 (41%)
		leucine-rich repeat	411..434	CDD:275380	3/22 (14%)
		leucine-rich repeat	435..455	CDD:275380	7/19 (37%)
		leucine-rich repeat	459..482	CDD:275380	5/22 (23%)
		leucine-rich repeat	483..505	CDD:275380	7/22 (32%)
		leucine-rich repeat	506..529	CDD:275380	6/22 (27%)
		LRR_8	528..588	CDD:290566	13/42 (31%)
		leucine-rich repeat	530..553	CDD:275380	5/22 (23%)
		leucine-rich repeat	554..574	CDD:275380	6/16 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54393
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010