Protein Alignment Sur-8 and Lap1

DIOPT Version :10

• Sequence 1: NP_001262665.1
• Gene: Sur-8 / 42093
• FlyBaseID: FBgn0038504
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: NP_611007.1
• Gene: Lap1 / 36670
• FlyBaseID: FBgn0033984
• Length: 849
• Species: Drosophila melanogaster
• Alignment Length: 461
• Identity: 133/461 - (28%)
• Similarity: 223/461 - (48%)
• Gaps: 64/461 - (13%)

  Fly   154 LQRC-------RDEGIKRLDLSKSSITVIPSTVKECVHLTELYLYSNKIGQLPPEIGCLVSLRNL 211
            |.:|       |:|.|.:||.|.:.:|..|...:....|.||||.:.::..|||::.....||.|
  Fly     4 LSKCFPCFKFKREEVIDKLDYSNTPLTDFPEVWQHERTLEELYLSTTRLQALPPQLFYCQGLRVL 68

  Fly   212 ALNENSLTSLPESLQNCSQLKVLDLRHNKLAEIPPVIYRLRSLTTLYLRFNRITAVADDLRQLVN 276
            .:|.|:|.|:|:::.:..||:.|||..|.:..:|..|...:.||.|.|..|.:..:.|.:..|::
  Fly    69 HVNSNNLESIPQAIGSLRQLQHLDLNRNLIVNVPEEIKSCKHLTHLDLSCNSLQRLPDAITSLIS 133

  Fly   277 LTMLSLRENKIRELGSAIGALVNLTTLDVSHNHLEHLPEDIGNCVNLSALDLQHNELLDIPDSIG 341
            |..|.|.|..:..|.:..|.||||..|::..|:|..||:.:...:||..||:..||..::|:.:|
  Fly   134 LQELLLNETYLEFLPANFGRLVNLRILELRLNNLMTLPKSMVRLINLQRLDIGGNEFTELPEVVG 198

  Fly   342 NLKSLVRLGMRYNRLSSVPATLKNCKSMDEFNVEGNGITQLPDGMLASLSGLTTITLSRNQFASY 406
            .||||..|.:.:|::..|.|.:...:.:..|...||.:..||..:
  Fly   199 ELKSLRELWIDFNQIRRVSANIGKLRDLQHFEANGNLLDTLPSEL-------------------- 243

  Fly   407 PTGGPAQFTNVYSINLEHNRIDKIPYGIFSRAKGLTKLNMKENMLTALPLDIGTWVNMVELNLAT 471
                                         |..:.:..|::..|.|.|.|..:|...::|.....:
  Fly   244 -----------------------------SNWRNVEVLSICSNSLEAFPFSVGMLKSLVTFKCES 279

  Fly   472 NALQKLPDDIMNLQNLEILILSNNMLKKIPNTIGNLRKLRILDLEENRIEVLPHEIGLLHELQRL 536
            |.|.:|||.|..|:.||.|:||:|.|.::|:|||.||.||.|..::|::..||.|:....:|..|
  Fly   280 NGLTELPDSISYLEQLEELVLSHNKLIRLPSTIGMLRSLRFLFADDNQLRQLPDELCSCQQLSVL 344

  Fly   537 ILQTNQITMLPRSIGHLGNLTHLSVSENNLQFLPEEIGSLESLENLYINQNPGLEKLPFELALCQ 601
            .:..||::.||::||:|..:..|:|..|.:..||..:.:|.:|.:::::.|.....:|
  Fly   345 SVANNQLSALPQNIGNLSKMKVLNVVNNYINALPVSMLNLVNLTSMWLSDNQSQPLVP------- 402

  Fly   602 NLKYLN 607
             |:||:
  Fly   403 -LQYLD 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sur-8	NP_001262665.1	leucine-rich repeat	163..184	CDD:275380	5/20 (25%)
		LRR	185..535	CDD:443914	103/349 (30%)
		leucine-rich repeat	185..207	CDD:275380	8/21 (38%)
		leucine-rich repeat	208..230	CDD:275380	8/21 (38%)
		leucine-rich repeat	231..253	CDD:275380	7/21 (33%)
		leucine-rich repeat	254..276	CDD:275380	7/21 (33%)
		leucine-rich repeat	277..299	CDD:275380	7/21 (33%)
		leucine-rich repeat	300..322	CDD:275380	6/21 (29%)
		leucine-rich repeat	323..345	CDD:275380	8/21 (38%)
		leucine-rich repeat	346..368	CDD:275380	5/21 (24%)
		leucine-rich repeat	369..392	CDD:275380	5/22 (23%)
		leucine-rich repeat	417..440	CDD:275380	1/22 (5%)
		leucine-rich repeat	441..486	CDD:275380	14/44 (32%)
		PPP1R42	472..617	CDD:455733	48/136 (35%)
		leucine-rich repeat	487..507	CDD:275380	11/19 (58%)
		leucine-rich repeat	510..532	CDD:275380	7/21 (33%)
		leucine-rich repeat	556..578	CDD:275380	6/21 (29%)
		leucine-rich repeat	603..626	CDD:275380	3/5 (60%)
Lap1	NP_611007.1	LRR	12..407	CDD:443914	130/451 (29%)
		leucine-rich repeat	21..41	CDD:275380	5/19 (26%)
		leucine-rich repeat	42..64	CDD:275380	8/21 (38%)
		leucine-rich repeat	65..87	CDD:275380	8/21 (38%)
		leucine-rich repeat	88..110	CDD:275380	7/21 (33%)
		leucine-rich repeat	111..133	CDD:275380	7/21 (33%)
		leucine-rich repeat	134..156	CDD:275380	7/21 (33%)
		leucine-rich repeat	157..179	CDD:275380	6/21 (29%)
		leucine-rich repeat	180..202	CDD:275380	8/21 (38%)
		leucine-rich repeat	203..225	CDD:275380	5/21 (24%)
		leucine-rich repeat	226..248	CDD:275380	6/70 (9%)
		leucine-rich repeat	272..294	CDD:275380	8/21 (38%)
		leucine-rich repeat	295..317	CDD:275380	12/21 (57%)
		leucine-rich repeat	318..340	CDD:275380	7/21 (33%)
		leucine-rich repeat	364..386	CDD:275380	6/21 (29%)
		PDZ_canonical	778..846	CDD:467153