Protein Alignment Sur-8 and fliI

DIOPT Version :10

• Sequence 1: NP_001262665.1
• Gene: Sur-8 / 42093
• FlyBaseID: FBgn0038504
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: NP_525097.1
• Gene: fliI / 33110
• FlyBaseID: FBgn0000709
• Length: 1256
• Species: Drosophila melanogaster
• Alignment Length: 479
• Identity: 136/479 - (28%)
• Similarity: 216/479 - (45%)
• Gaps: 94/479 - (19%)

  Fly   162 IKRLDLSKSSIT-VIPSTVKECVHLTELYLYSNKIGQLPPEIGCLVSLRNLALNENSLTSLPESL 225
            ::.:|.:|:..: ..||::::...:..|.|...::.::|.|:|.|..|.:|:||.|.|..:...|
  Fly     7 VRGVDFTKNDFSATFPSSMRQMSRVQWLTLDRTQLAEIPEELGHLQKLEHLSLNHNRLEKIFGEL 71

  Fly   226 QNCSQLKVLDLRHNKL--AEIPPVIYRLRSLTTLYLRFNRITAVADDLRQLVNLTMLSLRENKIR 288
            ...|.|:.||||||:|  :.|||.::.|..||||.|..|::..|.:.|.:..||.:|:|..|:|.
  Fly    72 TELSCLRSLDLRHNQLKNSGIPPELFHLEELTTLDLSHNKLKEVPEGLERAKNLIVLNLSNNQIE 136

  Fly   289 ELGSAIGA-LVNLTTLDVSHNHLEHLPEDIGNCVNLSALDLQHNELLDIPDSIGNLKSLVRLGMR 352
            .:.:.:.. |.:|..||:|||.||.||......:||..|||.||.|           .|.:|
  Fly   137 SIPTPLFIHLTDLLFLDLSHNRLETLPPQTRRLINLKTLDLSHNPL-----------ELFQL--- 187

  Fly   353 YNRLSSVPATLKNCKSMDEFNVEGNGITQLPDGMLASLSGLTTITLSRNQ--FASYPTGGPAQFT 415
                                       .|||     ||..|..:.:|..|  ..::||...: ..
  Fly   188 ---------------------------RQLP-----SLQSLEVLKMSGTQRTLLNFPTSIDS-LA 219

  Fly   416 NVYSINLEHNRIDKIP---YGIFSRAKGLTKLNMKENMLTALPLDIGTWVNMVELNLATNALQKL 477
            |:..::|.||.:.|:|   |.:.:    |.:||:.:|.||.|...:..|..:..|||:.|.|..|
  Fly   220 NLCELDLSHNSLPKLPDCVYNVVT----LVRLNLSDNELTELTAGVELWQRLESLNLSRNQLVAL 280

  Fly   478 PDDIMNLQNLEILILSNNML--KKIPNTIGNLRKLRILDLEENRIEVLPHEIGLLHELQRLILQT 540
            |..:..|..|..|::::|.|  :.||:.||.|..|.:.....|.:|
  Fly   281 PAALCKLPKLRRLLVNDNKLNFEGIPSGIGKLGALEVFSAANNLLE------------------- 326

  Fly   541 NQITMLPRSIGHLGNLTHLSVSENNLQFLPEEIGSLESLENLYINQNPGL--EKLPFELALCQNL 603
                |:|..:...|.|..|::|.|.|..||:.|..||.|:.|.:..||.|  ...|.|.:...:|
  Fly   327 ----MVPEGLCRCGALKQLNLSCNRLITLPDAIHLLEGLDQLDLRNNPELVMPPKPSEASKATSL 387

  Fly   604 KYLNID-------KCPLSTIPPEI 620
            ::.|||       :...:.:||.:
  Fly   388 EFYNIDFSLQTQLRLAGAAVPPSM 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sur-8	NP_001262665.1	leucine-rich repeat	163..184	CDD:275380	4/21 (19%)
		LRR	185..535	CDD:443914	106/359 (30%)
		leucine-rich repeat	185..207	CDD:275380	6/21 (29%)
		leucine-rich repeat	208..230	CDD:275380	7/21 (33%)
		leucine-rich repeat	231..253	CDD:275380	12/23 (52%)
		leucine-rich repeat	254..276	CDD:275380	8/21 (38%)
		leucine-rich repeat	277..299	CDD:275380	6/22 (27%)
		leucine-rich repeat	300..322	CDD:275380	10/21 (48%)
		leucine-rich repeat	323..345	CDD:275380	7/21 (33%)
		leucine-rich repeat	346..368	CDD:275380	2/21 (10%)
		leucine-rich repeat	369..392	CDD:275380	5/22 (23%)
		leucine-rich repeat	417..440	CDD:275380	6/25 (24%)
		leucine-rich repeat	441..486	CDD:275380	16/44 (36%)
		PPP1R42	472..617	CDD:455733	41/155 (26%)
		leucine-rich repeat	487..507	CDD:275380	8/21 (38%)
		leucine-rich repeat	510..532	CDD:275380	3/21 (14%)
		leucine-rich repeat	556..578	CDD:275380	9/21 (43%)
		leucine-rich repeat	603..626	CDD:275380	6/25 (24%)
fliI	NP_525097.1	leucine-rich repeat	7..30	CDD:275380	4/22 (18%)
		leucine-rich repeat	31..53	CDD:275380	6/21 (29%)
		LRR	33..405	CDD:443914	130/445 (29%)
		leucine-rich repeat	54..76	CDD:275380	7/21 (33%)
		leucine-rich repeat	77..101	CDD:275380	12/23 (52%)
		leucine-rich repeat	102..124	CDD:275380	8/21 (38%)
		leucine-rich repeat	125..148	CDD:275380	6/22 (27%)
		leucine-rich repeat	149..171	CDD:275380	10/21 (48%)
		leucine-rich repeat	172..195	CDD:275380	14/68 (21%)
		leucine-rich repeat	196..220	CDD:275380	5/24 (21%)
		leucine-rich repeat	221..243	CDD:275380	6/21 (29%)
		leucine-rich repeat	244..266	CDD:275380	8/21 (38%)
		leucine-rich repeat	267..289	CDD:275380	8/21 (38%)
		leucine-rich repeat	290..314	CDD:275380	9/23 (39%)
		leucine-rich repeat	315..335	CDD:275380	5/42 (12%)
		leucine-rich repeat	338..360	CDD:275378	9/21 (43%)
		gelsolin_S1_like	491..602	CDD:200446
		gelsolin_like	618..706	CDD:200436
		gelsolin_S3_like	729..828	CDD:200448
		gelsolin_like	920..1015	CDD:200436
		gelsolin_S5_like	1037..1141	CDD:200444
		gelsolin_S6_like	1151..1250	CDD:200447