DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sur-8 and lrrc57

DIOPT Version :9

Sequence 1:NP_001262665.1 Gene:Sur-8 / 42093 FlyBaseID:FBgn0038504 Length:694 Species:Drosophila melanogaster
Sequence 2:NP_001120199.1 Gene:lrrc57 / 100145243 XenbaseID:XB-GENE-5779276 Length:238 Species:Xenopus tropicalis


Alignment Length:243 Identity:76/243 - (31%)
Similarity:129/243 - (53%) Gaps:18/243 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   357 SSVPATLKNCKSMDEFNVEGNGITQLPDGMLASLSG-LTTITLSRNQFASYPTGGP--AQFTNVY 418
            |:..|.|:..:....|.:.|.|:|:.|:. |..||| |.||.||.|:..:.|   |  .:|..:.
 Frog     4 SAFKAHLETAQKTGVFQLTGKGLTEFPED-LQRLSGNLRTIDLSSNKIEALP---PMVGKFNLLK 64

  Fly   419 SINLEHNRIDKIPYGIFSRAKGLTKLNMKENMLTALPLDIGTWVNMVELNLATNALQKLPDDIMN 483
            |:.|.:|||.::|..: .|.|.|..|::..|.::.:|.|....:.:..|||:.|.|:.||..:..
 Frog    65 SLTLNNNRISRLPDEL-CRLKKLETLHLSGNQISQIPADFVQLLALKTLNLSGNQLRTLPAQLCK 128

  Fly   484 LQNLEILILSNNMLKKIPNTIGNLRKLRILDLEENRIEVLPHEIGLLHELQRLILQTN--QITML 546
            |:||:::.||.|.::.||:.:..|:.:. |:|.:|:|..:...|.....|:.|.|:.|  :::||
 Frog   129 LRNLDVVDLSKNRIQAIPDEVSGLQAIE-LNLNQNQISQISVHISHCPRLKVLRLEENCLELSML 192

  Fly   547 PRSIGHLGNLTHLSVSENNLQFLPEEIGSLESLE--NLYINQNPGLEK 592
            |:||.....::.|:| |.||    .||..|..||  :.|:.:...:.|
 Frog   193 PQSILGDSQISLLAV-EGNL----FEIKKLRDLEGYDKYMERFTAIRK 235

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sur-8NP_001262665.1 leucine-rich repeat 163..184 CDD:275380
leucine-rich repeat 185..207 CDD:275380
LRR_RI 204..401 CDD:238064 17/44 (39%)
LRR_8 207..264 CDD:290566
leucine-rich repeat 208..230 CDD:275380
leucine-rich repeat 231..253 CDD:275380
LRR_8 252..310 CDD:290566
leucine-rich repeat 254..276 CDD:275380
leucine-rich repeat 277..299 CDD:275380
LRR_8 299..356 CDD:290566
leucine-rich repeat 300..322 CDD:275380
leucine-rich repeat 323..345 CDD:275380
LRR_8 344..403 CDD:290566 18/46 (39%)
leucine-rich repeat 346..368 CDD:275380 3/10 (30%)
leucine-rich repeat 369..392 CDD:275380 7/22 (32%)
LRR_RI <379..566 CDD:238064 61/191 (32%)
leucine-rich repeat 417..440 CDD:275380 7/22 (32%)
leucine-rich repeat 441..486 CDD:275380 13/44 (30%)
LRR_8 463..520 CDD:290566 19/56 (34%)
leucine-rich repeat 487..507 CDD:275380 6/19 (32%)
leucine-rich repeat 510..532 CDD:275380 5/21 (24%)
LRR_8 532..588 CDD:290566 20/59 (34%)
leucine-rich repeat 556..578 CDD:275380 8/21 (38%)
leucine-rich repeat 603..626 CDD:275380
lrrc57NP_001120199.1 LRR <20..>168 CDD:227223 50/153 (33%)
leucine-rich repeat 40..62 CDD:275380 9/24 (38%)
leucine-rich repeat 63..85 CDD:275380 7/22 (32%)
leucine-rich repeat 86..108 CDD:275380 5/21 (24%)
leucine-rich repeat 109..131 CDD:275380 8/21 (38%)
leucine-rich repeat 132..154 CDD:275380 7/21 (33%)
leucine-rich repeat 155..176 CDD:275380 5/21 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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