Protein Alignment CREG and CREG2

DIOPT Version :10

• Sequence 1: NP_524385.2
• Gene: CREG / 42092
• FlyBaseID: FBgn0025456
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: NP_722578.1
• Gene: CREG2 / 200407
• HGNCID: 14272
• Length: 290
• Species: Homo sapiens
• Alignment Length: 202
• Identity: 51/202 - (25%)
• Similarity: 98/202 - (48%)
• Gaps: 15/202 - (7%)

  Fly    18 LDPSSGYSRRKDERI---IREYKRE--QELN-------HAKIARDLVHRANWAAVGSLSTNERVK 70
            |.|.:|.:|.:....   :..|:||  |..:       .|..||.|.|.:.|..:.::||:::::
Human    85 LRPRAGAARARPPPAPPGMFSYRREGGQTASAPPGPRLRAATARSLAHASVWGCLATVSTHKKIQ 149

  Fly    71 GYPMVNIISIDDSDANNRSTGRIRFLLTDLDFTGPDWQKDNKVTLLFSDEQTLRCKEGGKDPMEP 135
            |.|..|.:.:.|...|| |||...|.:|..|....|..|:...:|:..:.:...|::...||.:|
Human   150 GLPFGNCLPVSDGPFNN-STGIPFFYMTAKDPVVADLMKNPMASLMLPESEGEFCRKNIVDPEDP 213

  Fly   136 TCARSMISGQVKKMDPSDKSYQPSLDAYVRRHPAAINWVKAHNFYLCELEISNIFVLDFYGGPHK 200
            .|.:..::||:..:.|.:..:  :..|...|||....|.:.:.::..::.|.:|::..:|||...
Human   214 RCVQLTLTGQMIAVSPEEVEF--AKQAMFSRHPGMRKWPRQYEWFFMKMRIEHIWLQKWYGGASS 276

  Fly   201 VSASDYY 207
            :|..:|:
Human   277 ISREEYF 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CREG	NP_524385.2	Pyrid_oxidase_2	39..208	CDD:404723	45/178 (25%)
CREG2	NP_722578.1	Pyrid_oxidase_2	118..284	CDD:404723	43/169 (25%)