DRSC/TRiP Functional Genomics Resources

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Protein Alignment sds22 and NUD1

DIOPT Version :9

Sequence 1:NP_650619.1 Gene:sds22 / 42091 FlyBaseID:FBgn0028992 Length:326 Species:Drosophila melanogaster
Sequence 2:NP_015018.3 Gene:NUD1 / 854555 SGDID:S000005900 Length:851 Species:Saccharomyces cerevisiae


Alignment Length:331 Identity:76/331 - (22%)
Similarity:145/331 - (43%) Gaps:78/331 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 IDPDCYEL------DLNHR--RIEKLENF-----EPL--TRIERLFLR----------WNLIKKI 76
            :|...|||      |:.:|  :|::.||.     .||  .:...||.:          ....:.|
Yeast   354 LDKKAYELTSTKPGDVGYRQKKIQEEENLANSDDTPLDTPKFNDLFTKNGTRAKVKGQMRTSRSI 418

  Fly    77 ENLSSLKTLIELELYDNQITKIENLDDLPHLEVLDISFNRLTKIENLDKLVKL------------ 129
            .|.:.|:...:|:.:     ..|.::|:..:..::.|||...|     :|:.:            
Yeast   419 SNSNLLEAHKKLKTF-----PAERVEDITSISEVNTSFNETEK-----QLISILTSKLSGSPSYD 473

  Fly   130 ---EKVYFVSNRITQIENL----DMLTNLTMLELGDNKLKKIENIEMLVNLRQLFLGKNKIAKIE 187
               ||:..|.....:::|:    .:|.|:.:|.|.||::..:|.|..  |:.|||...|||....
Yeast   474 SDWEKILKVDLSRGKLKNMFGMQRLLPNVLVLNLSDNEMNTLEGIPS--NVVQLFCSNNKITSAH 536

  Fly   188 -NLDTLVNLEILSLQANRI-VKIENLEKLANLRELYVSENGVETIENLSENTKLETLDLAKNRLK 250
             :|....:||.|.|..|.: ..::.|....:|:|:.:|.|.::::|.:. :::::.|:|:.|.:.
Yeast   537 CSLAGFHDLECLDLSYNLLNTSLKFLSLCHHLQEVNLSYNSIQSLEGIG-SSRMKKLNLSNNEIN 600

  Fly   251 GIANLEKLELLEELWLNHNGVDDWKDIELLKVNK-------------ALQTIYLEYNPLAKDVRY 302
            ||.:.|:|.|     .|::.|..|..:|:|.::.             .|:.:.|..|||...|. 
Yeast   601 GIIDFEQLIL-----TNNSVVGGWLTVEVLDLSNNNIIGVRNINCLPRLKVLNLNGNPLVSIVE- 659

  Fly   303 RSKLRD 308
            .||:.:
Yeast   660 SSKMEN 665

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sds22NP_650619.1 leucine-rich repeat 43..62 CDD:275380 9/33 (27%)
LRR_8 61..117 CDD:290566 11/65 (17%)
leucine-rich repeat 63..84 CDD:275380 5/30 (17%)
LRR_4 83..125 CDD:289563 7/41 (17%)
leucine-rich repeat 85..106 CDD:275380 3/20 (15%)
LRR_8 105..183 CDD:290566 22/96 (23%)
leucine-rich repeat 107..128 CDD:275380 5/20 (25%)
LRR_4 128..168 CDD:289563 11/58 (19%)
leucine-rich repeat 129..150 CDD:275380 5/39 (13%)
LRR_4 149..189 CDD:289563 14/40 (35%)
leucine-rich repeat 151..172 CDD:275380 6/20 (30%)
leucine-rich repeat 173..194 CDD:275380 7/21 (33%)
LRR_8 194..249 CDD:290566 14/55 (25%)
LRR_4 194..235 CDD:289563 11/41 (27%)
leucine-rich repeat 195..216 CDD:275380 6/21 (29%)
leucine-rich repeat 217..238 CDD:275380 5/20 (25%)
NUD1NP_015018.3 LRR <440..662 CDD:227223 56/235 (24%)
leucine-rich repeat 522..544 CDD:275380 7/21 (33%)
leucine-rich repeat 545..567 CDD:275380 6/21 (29%)
PPP1R42 557..784 CDD:411060 27/116 (23%)
leucine-rich repeat 568..588 CDD:275380 5/20 (25%)
leucine-rich repeat 589..621 CDD:275380 11/36 (31%)
leucine-rich repeat 622..643 CDD:275380 2/20 (10%)
leucine-rich repeat 699..738 CDD:275380
leucine-rich repeat 739..768 CDD:275380
leucine-rich repeat 794..806 CDD:275378
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0531
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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