DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment sds22 and LRRCC1

DIOPT Version :9

Sequence 1:NP_650619.1 Gene:sds22 / 42091 FlyBaseID:FBgn0028992 Length:326 Species:Drosophila melanogaster
Sequence 2:XP_016869409.1 Gene:LRRCC1 / 85444 HGNCID:29373 Length:1046 Species:Homo sapiens


Alignment Length:213 Identity:71/213 - (33%)
Similarity:105/213 - (49%) Gaps:20/213 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   119 KIENLDKLVKLEKVYFVSNRITQIENLDMLTNLTMLELGDNKLKKIENIEMLVNLRQLFLGKNKI 183
            ::||.|.......|.|:...:..|..|.:.:.|..:.|..|.:.|||.|:.:.||:.|.|..|:|
Human    13 EVENEDGDSSCGDVCFMDKGLQSISELSLDSTLHAVNLHCNNISKIEAIDHIWNLQHLDLSSNQI 77

  Fly   184 AKIENLDTLVNLEILSLQANRIVKIENLEKLANLRELYVSENGVETIENL----SENTKLETLDL 244
            ::||.|:||..|..|:|..|.|.|:|.||:|.||..|.||.|.::.:..|    ....||..:||
Human    78 SRIEGLNTLTKLCTLNLSCNLITKVEGLEELINLTRLNVSYNHIDDLSGLIPLHGIKHKLRYIDL 142

  Fly   245 AKNRLKGIANLEK----LELLEELWLNHNGVDDWKDIELLKVNKALQTIYLEYNPLAKDVR-YRS 304
            ..||:..|.:|.:    |..|..|.|..:| ||.....|  ...:|.|:     .|..::| ||:
Human   143 HSNRIDSIHHLLQCMVGLHFLTNLILEKDG-DDNPVCRL--PGTSLNTV-----TLPSELRGYRA 199

  Fly   305 KLRDILPQLQKIDATLCK 322
            .:...||||:.:|   ||
Human   200 VILQTLPQLRILD---CK 214

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sds22NP_650619.1 leucine-rich repeat 43..62 CDD:275380
LRR_8 61..117 CDD:290566
leucine-rich repeat 63..84 CDD:275380
LRR_4 83..125 CDD:289563 2/5 (40%)
leucine-rich repeat 85..106 CDD:275380
LRR_8 105..183 CDD:290566 19/63 (30%)
leucine-rich repeat 107..128 CDD:275380 3/8 (38%)
LRR_4 128..168 CDD:289563 10/39 (26%)
leucine-rich repeat 129..150 CDD:275380 4/20 (20%)
LRR_4 149..189 CDD:289563 15/39 (38%)
leucine-rich repeat 151..172 CDD:275380 7/20 (35%)
leucine-rich repeat 173..194 CDD:275380 10/20 (50%)
LRR_8 194..249 CDD:290566 22/58 (38%)
LRR_4 194..235 CDD:289563 17/44 (39%)
leucine-rich repeat 195..216 CDD:275380 10/20 (50%)
leucine-rich repeat 217..238 CDD:275380 6/24 (25%)
LRRCC1XP_016869409.1 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0531
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.