DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sds22 and Lrriq3

DIOPT Version :9

Sequence 1:	NP_650619.1	Gene:	sds22 / 42091	FlyBaseID:	FBgn0028992	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_083214.2	Gene:	Lrriq3 / 74435	MGIID:	1921685	Length:	633	Species:	Mus musculus

Alignment Length:	178	Identity:	40/178 - (22%)
Similarity:	79/178 - (44%)	Gaps:	22/178 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 LKKIENIEMLVNLRQLFLGKNKIAKIENLDTLVNLEILSLQANRIVKIEN---LEKLANLRELYV 222
            ||.:||::..::||......|.:..|:.|.:...|..|.|..|:|..:.:   ...|.||:.||:
Mouse    40 LKSMENLQTCISLRVCIFSNNFLTDIQPLQSCKKLIKLDLHGNQIKTLPDKNFWSGLKNLKLLYL 104

  Fly   223 SENGVETIENLS------ENTKLETLDLAKNRLKGIANLEKLELLEELW----LNHNGVDDWKDI 277
            .:||...::|:.      ....|...|...:..||..::    |:..:|    |:|:.:.|.:.|
Mouse   105 HDNGFSKLKNICVLSGCVSLIGLTMFDCPVSLKKGYRHV----LVNSIWPLKALDHHVISDEEII 165

  Fly   278 ELLKVNKALQT-----IYLEYNPLAKDVRYRSKLRDILPQLQKIDATL 320
            :..::.:..:|     .:..|..|.|...|..::::|...:.:|:..|
Mouse   166 QNWRLPERFKTFSPSLFFNLYPALIKGTTYEDEIKNIKHIISRINEIL 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sds22	NP_650619.1	leucine-rich repeat	43..62	CDD:275380
		LRR_8	61..117	CDD:290566
		leucine-rich repeat	63..84	CDD:275380
		LRR_4	83..125	CDD:289563
		leucine-rich repeat	85..106	CDD:275380
		LRR_8	105..183	CDD:290566	7/21 (33%)
		leucine-rich repeat	107..128	CDD:275380
		LRR_4	128..168	CDD:289563	4/6 (67%)
		leucine-rich repeat	129..150	CDD:275380
		LRR_4	149..189	CDD:289563	8/27 (30%)
		leucine-rich repeat	151..172	CDD:275380	4/10 (40%)
		leucine-rich repeat	173..194	CDD:275380	5/20 (25%)
		LRR_8	194..249	CDD:290566	15/63 (24%)
		LRR_4	194..235	CDD:289563	13/49 (27%)
		leucine-rich repeat	195..216	CDD:275380	6/23 (26%)
		leucine-rich repeat	217..238	CDD:275380	6/26 (23%)
Lrriq3	NP_083214.2	LRR_8	51..109	CDD:338972	16/57 (28%)
		LRR 1	51..72		5/20 (25%)
		leucine-rich repeat	52..73	CDD:275378	5/20 (25%)
		LRR 2	73..94		5/20 (25%)
		leucine-rich repeat	74..98	CDD:275378	6/23 (26%)
		LRR 3	98..119		7/20 (35%)
		leucine-rich repeat	99..112	CDD:275378	5/12 (42%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	324..343
		SidE	<459..630	CDD:289056
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900