DRSC/TRiP Functional Genomics Resources

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Protein Alignment sds22 and Lrrc56

DIOPT Version :9

Sequence 1:NP_650619.1 Gene:sds22 / 42091 FlyBaseID:FBgn0028992 Length:326 Species:Drosophila melanogaster
Sequence 2:XP_006536303.1 Gene:Lrrc56 / 70552 MGIID:1917802 Length:559 Species:Mus musculus


Alignment Length:196 Identity:54/196 - (27%)
Similarity:93/196 - (47%) Gaps:30/196 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   139 ITQIENLDMLTNLTMLELGDNKLKKIENIEM-LVNLRQLFLGKNKIAKIENLDT-LVNLEILSLQ 201
            :.|:::|.::..|.|..  |.:...:.|..: |.||.||.|..:.:..:.:|.| |.:|::|.|.
Mouse    69 LAQVDDLQLVRVLEMCV--DTRKNSLGNFGLYLPNLIQLKLNHSYLGSLRDLGTSLGHLQVLWLA 131

  Fly   202 ANRIVKIENLEKLANLRELYVSENGVETIENLSENTKLETLDLAKNRLKGIANLEKLELLEEL-W 265
            ...:..::.:.....|:|||||.|.:..:..|....:||.|||..|.::.:..:..|:|...| .
Mouse   132 RCGLTDLDGIGSFLELKELYVSYNNISDLSPLCLLEQLEVLDLEGNNVEDLGQMRYLQLCPRLAM 196

  Fly   266 LNHNGVDDWKDIELLK-----VNKALQTIYLEYNPLAKDVRYRSKLRDILPQLQKIDATLCKVPG 325
            |...|     ::..||     .|||.|    .||       ||::::.::|||..:|    :||.
Mouse   197 LTLEG-----NLVCLKPDPGPSNKAPQ----GYN-------YRAEVKKLIPQLHVLD----EVPT 241

  Fly   326 T 326
            |
Mouse   242 T 242

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sds22NP_650619.1 leucine-rich repeat 43..62 CDD:275380
LRR_8 61..117 CDD:290566
leucine-rich repeat 63..84 CDD:275380
LRR_4 83..125 CDD:289563
leucine-rich repeat 85..106 CDD:275380
LRR_8 105..183 CDD:290566 12/44 (27%)
leucine-rich repeat 107..128 CDD:275380
LRR_4 128..168 CDD:289563 6/28 (21%)
leucine-rich repeat 129..150 CDD:275380 2/10 (20%)
LRR_4 149..189 CDD:289563 10/40 (25%)
leucine-rich repeat 151..172 CDD:275380 5/21 (24%)
leucine-rich repeat 173..194 CDD:275380 7/21 (33%)
LRR_8 194..249 CDD:290566 17/54 (31%)
LRR_4 194..235 CDD:289563 11/40 (28%)
leucine-rich repeat 195..216 CDD:275380 3/20 (15%)
leucine-rich repeat 217..238 CDD:275380 8/20 (40%)
Lrrc56XP_006536303.1 internalin_A <99..>202 CDD:380193 31/107 (29%)
leucine-rich repeat 102..124 CDD:275380 7/21 (33%)
leucine-rich repeat 125..146 CDD:275380 3/20 (15%)
leucine-rich repeat 147..168 CDD:275380 8/20 (40%)
leucine-rich repeat 169..193 CDD:275380 8/23 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0531
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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