DRSC/TRiP Functional Genomics Resources

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Protein Alignment sds22 and lrguk

DIOPT Version :9

Sequence 1:NP_650619.1 Gene:sds22 / 42091 FlyBaseID:FBgn0028992 Length:326 Species:Drosophila melanogaster
Sequence 2:XP_021330922.1 Gene:lrguk / 559670 ZFINID:ZDB-GENE-050419-232 Length:739 Species:Danio rerio


Alignment Length:272 Identity:85/272 - (31%)
Similarity:130/272 - (47%) Gaps:27/272 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    73 IKKIENLSSLKTLIELELYDNQITKIENLDDLPHLEVLDISFNRLTKIENLDKLVKLEKVYFVSN 137
            :|.:..|.:...|.:|||..|:|..:..:..:|:|..||.|.|:||..........|::|.|..|
Zfish    49 LKNVSILCNYIYLQKLELPYNKIKDLSCVSHMPYLITLDASHNQLTDFFGFQPPKNLKEVNFSHN 113

  Fly   138 RITQIENLDMLTNLTMLELGDNKLKKIENIEMLVNLRQLFLGKNKIAKIENLDTLVNLEILSLQA 202
            ::|.:::|...::||.|.|..|....|..:|....|..|.|..|.|::|..||.| .|..|.|..
Zfish   114 QMTAMKDLSAYSSLTKLILDHNSFSVIRGLEKCKRLSHLSLAHNNISRIRGLDHL-PLRELCLAG 177

  Fly   203 NRIVKIENLEKLANLRELYVSENGVETIENLSENTKLETLDLAKN---RLKGIANLEKLELLEEL 264
            |.|.|||||:.|.||:.|.:|.|.::::..|.....|.|::|..|   .:|..|:|..|.||.|:
Zfish   178 NMINKIENLQTLHNLQVLDLSCNRIQSLTGLQNLRFLGTVNLESNLITEIKEAAHLHDLILLREI 242

  Fly   265 WLNHNGVDDWKDI---------ELLKVNKALQTIYLE--------YNPLAKDVRYRSKLRDILPQ 312
            .|..|.|.|..|.         .|:.::|  ||:..|        |:|..:.|..|..:..::.|
Zfish   243 NLLKNPVQDHDDYRIAVIFLLQHLILLDK--QTVTAEEKVAAVNKYDPPLEVVAARDHMTHLVYQ 305

  Fly   313 LQK----IDATL 320
            |.:    .|:||
Zfish   306 LMQPQVIFDSTL 317

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sds22NP_650619.1 leucine-rich repeat 43..62 CDD:275380
LRR_8 61..117 CDD:290566 14/43 (33%)
leucine-rich repeat 63..84 CDD:275380 2/10 (20%)
LRR_4 83..125 CDD:289563 14/41 (34%)
leucine-rich repeat 85..106 CDD:275380 6/20 (30%)
LRR_8 105..183 CDD:290566 25/77 (32%)
leucine-rich repeat 107..128 CDD:275380 7/20 (35%)
LRR_4 128..168 CDD:289563 12/39 (31%)
leucine-rich repeat 129..150 CDD:275380 6/20 (30%)
LRR_4 149..189 CDD:289563 13/39 (33%)
leucine-rich repeat 151..172 CDD:275380 7/20 (35%)
leucine-rich repeat 173..194 CDD:275380 9/20 (45%)
LRR_8 194..249 CDD:290566 21/57 (37%)
LRR_4 194..235 CDD:289563 17/40 (43%)
leucine-rich repeat 195..216 CDD:275380 11/20 (55%)
leucine-rich repeat 217..238 CDD:275380 5/20 (25%)
lrgukXP_021330922.1 LRR <25..>247 CDD:227223 67/198 (34%)
leucine-rich repeat 61..82 CDD:275380 6/20 (30%)
leucine-rich repeat 83..104 CDD:275380 7/20 (35%)
leucine-rich repeat 105..126 CDD:275380 6/20 (30%)
leucine-rich repeat 127..148 CDD:275380 7/20 (35%)
leucine-rich repeat 149..168 CDD:275380 8/18 (44%)
leucine-rich repeat 170..191 CDD:275380 11/20 (55%)
leucine-rich repeat 192..210 CDD:275380 5/17 (29%)
leucine-rich repeat 211..238 CDD:275380 8/26 (31%)
GMPK 326..449 CDD:238026
Herpes_ICP4_C 520..>739 CDD:332854
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0531
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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