DRSC/TRiP Functional Genomics Resources

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Protein Alignment sds22 and TbCMF46

DIOPT Version :9

Sequence 1:NP_650619.1 Gene:sds22 / 42091 FlyBaseID:FBgn0028992 Length:326 Species:Drosophila melanogaster
Sequence 2:NP_609325.2 Gene:TbCMF46 / 34318 FlyBaseID:FBgn0032163 Length:566 Species:Drosophila melanogaster


Alignment Length:340 Identity:101/340 - (29%)
Similarity:163/340 - (47%) Gaps:80/340 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 MNEPEAAKTVSGIQVIPAEDVAS----------IEDIITIDPDCYELDLNHRRI----------- 51
            |:||.:::        |.||...          :|:|     :|.|..:..|::           
  Fly     1 MDEPVSSQ--------PGEDAVEETEEEPLRGFLEEI-----NCPEPGIIDRQMIETAYLEEGKK 52

  Fly    52 ---EKLENFEPLT--RIERLFLRWNLIKKIENLSSLKTLIELELYDNQITKIENLDDLPHLEVLD 111
               .:|...||:.  ||..:.|.:..|.:|::|..:..|.:|.|..|:|..||:|:.|..|:.|:
  Fly    53 GEARRLHQLEPVVYDRITTMRLEFKNILRIDHLWMMPNLTKLCLNCNKIEVIEHLEMLTALKDLN 117

  Fly   112 ISFNRLTKIENLDKLVKLEKVYFVSNRITQIENLDMLTNLTMLELGDNKLKKIENIEML---VNL 173
            :|||.:|:||||:|||||||:...||||.:|||:..|.||.:|.:|:|.:..:|.||.|   .:|
  Fly   118 LSFNYITRIENLEKLVKLEKLSLFSNRIRKIENIHTLQNLVILSIGNNLIDTVEGIERLRFVSSL 182

  Fly   174 RQLFLGKNKIAKIENLDTLVNLEILSL--QANR----IVKIENLEK-----LANLRELYVSE--- 224
            :.|.|..|.|||  ..|..::|.::::  |.|.    .:|.|..|:     ...|||:...:   
  Fly   183 KVLNLEGNPIAK--QPDFPLSLYVIAILPQLNYYEYVFIKTETREEAQKRFYRELREIEDKQERE 245

  Fly   225 -NGVETIENLSENTKLETLDLAK-NRLKG--IANLEKLELLEELWLNHNGVDDWKDIELLKVNKA 285
             .|:||          |..::|: :||..  :.:|:.::|.:.||.     ||.....|:.|...
  Fly   246 IQGLET----------EAREMAEADRLASSFVEHLDGMQLYDSLWR-----DDEDGRILMLVGAP 295

  Fly   286 LQTIYLEYNPLAKDV 300
            .|.:..||   :|||
  Fly   296 AQELCEEY---SKDV 307

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sds22NP_650619.1 leucine-rich repeat 43..62 CDD:275380 5/34 (15%)
LRR_8 61..117 CDD:290566 20/57 (35%)
leucine-rich repeat 63..84 CDD:275380 5/20 (25%)
LRR_4 83..125 CDD:289563 19/41 (46%)
leucine-rich repeat 85..106 CDD:275380 9/20 (45%)
LRR_8 105..183 CDD:290566 38/80 (48%)
leucine-rich repeat 107..128 CDD:275380 12/20 (60%)
LRR_4 128..168 CDD:289563 18/39 (46%)
leucine-rich repeat 129..150 CDD:275380 11/20 (55%)
LRR_4 149..189 CDD:289563 16/42 (38%)
leucine-rich repeat 151..172 CDD:275380 8/23 (35%)
leucine-rich repeat 173..194 CDD:275380 8/20 (40%)
LRR_8 194..249 CDD:290566 14/70 (20%)
LRR_4 194..235 CDD:289563 12/55 (22%)
leucine-rich repeat 195..216 CDD:275380 6/31 (19%)
leucine-rich repeat 217..238 CDD:275380 6/24 (25%)
TbCMF46NP_609325.2 leucine-rich repeat 69..90 CDD:275378 5/20 (25%)
LRR_8 89..145 CDD:290566 28/55 (51%)
LRR_4 89..131 CDD:289563 19/41 (46%)
leucine-rich repeat 91..112 CDD:275378 9/20 (45%)
leucine-rich repeat 113..134 CDD:275378 12/20 (60%)
LRR_8 134..192 CDD:290566 25/57 (44%)
LRR_4 134..174 CDD:289563 18/39 (46%)
leucine-rich repeat 135..156 CDD:275378 11/20 (55%)
leucine-rich repeat 157..181 CDD:275378 8/23 (35%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45447149
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0531
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45973
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
43.840

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