DRSC/TRiP Functional Genomics Resources

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Protein Alignment sds22 and Lrrc49

DIOPT Version :9

Sequence 1:NP_650619.1 Gene:sds22 / 42091 FlyBaseID:FBgn0028992 Length:326 Species:Drosophila melanogaster
Sequence 2:NP_001127941.1 Gene:Lrrc49 / 300763 RGDID:1309466 Length:686 Species:Rattus norvegicus


Alignment Length:244 Identity:74/244 - (30%)
Similarity:130/244 - (53%) Gaps:24/244 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    76 IENLSSLKTLI--ELELYDNQITKIENLDDLPHLEVLDISFNRLTKIENLDKLVKLEKVYFVSNR 138
            ::..|..|||.  .|.|...::|....:|...||.:|:                      |..|.
  Rat    81 LQRSSEEKTLYSDRLTLERQKLTVCPIIDGEEHLRLLN----------------------FQHNF 123

  Fly   139 ITQIENLDMLTNLTMLELGDNKLKKIENIEMLVNLRQLFLGKNKIAKIENLDTLVNLEILSLQAN 203
            ||:|:|:..|..|..|:|.||::::|..:..|.:||.|.||||:|.||.||:.|.||::|.|..|
  Rat   124 ITRIQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISNLENLKNLDVLDLHGN 188

  Fly   204 RIVKIENLEKLANLRELYVSENGVETIENLSENTKLETLDLAKNRLKGIANLEKLELLEELWLNH 268
            :|.||||:..|.:||.|.::.|.:..::||:....|..|:|..|::..:.:::.|..|:.|:|:.
  Rat   189 QITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHNQITFVRDVDNLPCLQRLFLSF 253

  Fly   269 NGVDDWKDIELLKVNKALQTIYLEYNPLAKDVRYRSKLRDILPQLQKID 317
            |.:..::.:..|..:.:|..|..:.||:|::..|:..:...:.||:::|
  Rat   254 NNITSFESVSCLAESTSLSDITFDGNPIAQESWYKHTVLQNMMQLRQLD 302

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sds22NP_650619.1 leucine-rich repeat 43..62 CDD:275380
LRR_8 61..117 CDD:290566 11/42 (26%)
leucine-rich repeat 63..84 CDD:275380 1/7 (14%)
LRR_4 83..125 CDD:289563 10/43 (23%)
leucine-rich repeat 85..106 CDD:275380 5/22 (23%)
LRR_8 105..183 CDD:290566 24/77 (31%)
leucine-rich repeat 107..128 CDD:275380 2/20 (10%)
LRR_4 128..168 CDD:289563 13/39 (33%)
leucine-rich repeat 129..150 CDD:275380 7/20 (35%)
LRR_4 149..189 CDD:289563 17/39 (44%)
leucine-rich repeat 151..172 CDD:275380 7/20 (35%)
leucine-rich repeat 173..194 CDD:275380 13/20 (65%)
LRR_8 194..249 CDD:290566 21/54 (39%)
LRR_4 194..235 CDD:289563 17/40 (43%)
leucine-rich repeat 195..216 CDD:275380 10/20 (50%)
leucine-rich repeat 217..238 CDD:275380 6/20 (30%)
Lrrc49NP_001127941.1 leucine-rich repeat 94..111 CDD:275380 4/16 (25%)
LRR_4 112..153 CDD:289563 16/62 (26%)
leucine-rich repeat 114..135 CDD:275380 9/42 (21%)
LRR_4 134..176 CDD:289563 19/41 (46%)
leucine-rich repeat 136..157 CDD:275380 7/20 (35%)
LRR_8 156..212 CDD:290566 28/55 (51%)
LRR_4 156..198 CDD:289563 23/41 (56%)
leucine-rich repeat 158..179 CDD:275380 13/20 (65%)
LRR_4 178..220 CDD:289563 17/41 (41%)
leucine-rich repeat 180..201 CDD:275380 10/20 (50%)
LRR_8 202..256 CDD:290566 15/53 (28%)
leucine-rich repeat 202..223 CDD:275380 6/20 (30%)
LRR_4 223..263 CDD:289563 9/39 (23%)
leucine-rich repeat 224..245 CDD:275380 5/20 (25%)
leucine-rich repeat 246..270 CDD:275380 5/23 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0531
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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