DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sds22 and Lrguk

DIOPT Version :9

Sequence 1:	NP_650619.1	Gene:	sds22 / 42091	FlyBaseID:	FBgn0028992	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	XP_017448017.1	Gene:	Lrguk / 296968	RGDID:	1308226	Length:	1271	Species:	Rattus norvegicus

Alignment Length:	265	Identity:	77/265 - (29%)
Similarity:	129/265 - (48%)	Gaps:	28/265 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 ERLFLRWNL----IKKIENLSSLKTLIELELYDNQITKIENLDDLPHLEVLDISFNRLTKIENLD 124
            |:::...||    :..:..||....|.:|.|..|:|..:..:..:|:|..|:.|.||||...|..
  Rat   125 EQVYRNLNLSHCELIDVSILSGYVHLQKLNLSGNRIEDLSCVSCMPYLLELNASQNRLTTFFNFK 189

  Fly   125 KLVKL-EKVYFVSNRITQIENLDMLTNLTMLELGDNKLKKIENIEMLVNLRQLFLGKNKIAKIEN 188
            ....| :||.|.||:|:::.:|.....||.|.|.:|::::|..:|..::|..|.|..|:|..|:.
  Rat   190 PPQNLKQKVDFSSNQISEMYDLSAYHTLTQLILDNNEIEEITGLEKCISLTHLSLAGNRITTIKG 254

  Fly   189 LDTLVNLEILSLQANRIVKIENLEKLANLRELYVSENGVETIENLSENTKLETLDLAKNRLKGIA 253
            |.|| .:::||                      ||.|.:|||..|.|...|:.|||:.|::..:.
  Rat   255 LGTL-PIKVLS----------------------VSNNQIETITGLEELKALQNLDLSHNQISSLH 296

  Fly   254 NLEKLELLEELWLNHNGVDDWKDIELLKVNKALQTIYLEYNPLAKDVRYRSKLRDILPQLQKIDA 318
            .||..:|||.:.|..|.:.:..:||.::....|:.:.|..||:.....|...:..:|.:|.::|.
  Rat   297 GLENHDLLEVINLEDNKIKELSEIEYIENLPILRVLNLLRNPIQTKPEYWFFVIFMLLRLTELDQ 361

  Fly   319 TLCKV 323
            ...||
  Rat   362 QKIKV 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sds22	NP_650619.1	leucine-rich repeat	43..62	CDD:275380
		LRR_8	61..117	CDD:290566	15/56 (27%)
		leucine-rich repeat	63..84	CDD:275380	5/23 (22%)
		LRR_4	83..125	CDD:289563	14/41 (34%)
		leucine-rich repeat	85..106	CDD:275380	5/20 (25%)
		LRR_8	105..183	CDD:290566	28/78 (36%)
		leucine-rich repeat	107..128	CDD:275380	8/20 (40%)
		LRR_4	128..168	CDD:289563	14/40 (35%)
		leucine-rich repeat	129..150	CDD:275380	8/21 (38%)
		LRR_4	149..189	CDD:289563	13/39 (33%)
		leucine-rich repeat	151..172	CDD:275380	7/20 (35%)
		leucine-rich repeat	173..194	CDD:275380	9/20 (45%)
		LRR_8	194..249	CDD:290566	15/54 (28%)
		LRR_4	194..235	CDD:289563	9/40 (23%)
		leucine-rich repeat	195..216	CDD:275380	2/20 (10%)
		leucine-rich repeat	217..238	CDD:275380	8/20 (40%)
Lrguk	XP_017448017.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810