DRSC/TRiP Functional Genomics Resources

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Protein Alignment sds22 and Lrrc49

DIOPT Version :9

Sequence 1:NP_650619.1 Gene:sds22 / 42091 FlyBaseID:FBgn0028992 Length:326 Species:Drosophila melanogaster
Sequence 2:NP_663591.3 Gene:Lrrc49 / 102747 MGIID:2442689 Length:752 Species:Mus musculus


Alignment Length:244 Identity:74/244 - (30%)
Similarity:130/244 - (53%) Gaps:24/244 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    76 IENLSSLKTLI--ELELYDNQITKIENLDDLPHLEVLDISFNRLTKIENLDKLVKLEKVYFVSNR 138
            ::..|..|||.  .|.|...::|....:|...||.:|:                      |..|.
Mouse   147 LQRSSEEKTLYSDRLTLERQKLTVCPIIDGEEHLRLLN----------------------FQHNF 189

  Fly   139 ITQIENLDMLTNLTMLELGDNKLKKIENIEMLVNLRQLFLGKNKIAKIENLDTLVNLEILSLQAN 203
            ||:|:|:..|..|..|:|.||::::|..:..|.:||.|.||||:|.||.||:.|.||::|.|..|
Mouse   190 ITRIQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISNLENLKNLDVLDLHGN 254

  Fly   204 RIVKIENLEKLANLRELYVSENGVETIENLSENTKLETLDLAKNRLKGIANLEKLELLEELWLNH 268
            :|.||||:..|.:||.|.::.|.:..::||:....|..|:|..|::..:.:::.|..|:.|:|:.
Mouse   255 QITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHNQITFVRDVDNLPCLQRLFLSF 319

  Fly   269 NGVDDWKDIELLKVNKALQTIYLEYNPLAKDVRYRSKLRDILPQLQKID 317
            |.:..::.:..|..:.:|..|..:.||:|::..|:..:...:.||:::|
Mouse   320 NNITSFESVSCLAESTSLSDITFDGNPIAQESWYKHTVLQNMMQLRQLD 368

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sds22NP_650619.1 leucine-rich repeat 43..62 CDD:275380
LRR_8 61..117 CDD:290566 11/42 (26%)
leucine-rich repeat 63..84 CDD:275380 1/7 (14%)
LRR_4 83..125 CDD:289563 10/43 (23%)
leucine-rich repeat 85..106 CDD:275380 5/22 (23%)
LRR_8 105..183 CDD:290566 24/77 (31%)
leucine-rich repeat 107..128 CDD:275380 2/20 (10%)
LRR_4 128..168 CDD:289563 13/39 (33%)
leucine-rich repeat 129..150 CDD:275380 7/20 (35%)
LRR_4 149..189 CDD:289563 17/39 (44%)
leucine-rich repeat 151..172 CDD:275380 7/20 (35%)
leucine-rich repeat 173..194 CDD:275380 13/20 (65%)
LRR_8 194..249 CDD:290566 21/54 (39%)
LRR_4 194..235 CDD:289563 17/40 (43%)
leucine-rich repeat 195..216 CDD:275380 10/20 (50%)
leucine-rich repeat 217..238 CDD:275380 6/20 (30%)
Lrrc49NP_663591.3 leucine-rich repeat 160..177 CDD:275380 4/16 (25%)
LRR_4 178..219 CDD:289563 16/62 (26%)
leucine-rich repeat 180..201 CDD:275380 9/42 (21%)
LRR_4 200..242 CDD:289563 19/41 (46%)
leucine-rich repeat 202..223 CDD:275380 7/20 (35%)
LRR_8 222..278 CDD:290566 28/55 (51%)
LRR_4 222..264 CDD:289563 23/41 (56%)
leucine-rich repeat 224..245 CDD:275380 13/20 (65%)
LRR_4 244..286 CDD:289563 17/41 (41%)
leucine-rich repeat 246..267 CDD:275380 10/20 (50%)
LRR_8 268..322 CDD:290566 15/53 (28%)
leucine-rich repeat 268..289 CDD:275380 6/20 (30%)
LRR_4 289..329 CDD:289563 9/39 (23%)
leucine-rich repeat 290..311 CDD:275380 5/20 (25%)
leucine-rich repeat 312..336 CDD:275380 5/23 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0531
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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