Protein Alignment lute and BTBD6

DIOPT Version :10

• Sequence 1: NP_001262663.1
• Gene: lute / 42089
• FlyBaseID: FBgn0262871
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_001374496.1
• Gene: BTBD6 / 90135
• HGNCID: 19897
• Length: 538
• Species: Homo sapiens
• Alignment Length: 542
• Identity: 320/542 - (59%)
• Similarity: 385/542 - (71%)
• Gaps: 34/542 - (6%)

  Fly    75 RGGGGASPAGGGGGPSAAADHNIQITQPISAPSSPLASPGALNSSGSSSGGGAGSAGGISGSPTA 139
            |.|..|..|...|..:|.|....::...:.||:|..|:..|.:::|::.|..||..     ||
Human    30 RRGARARGAASTGAEAAPAAPPAKMAAELYAPASAAAADLANSNAGAAVGRKAGPR-----SP-- 87

  Fly   140 FCLPSSSAAAAVAAISATPTSGSGSYVCSAGTNWHFAAVAASNAIDTADPNWQASKATVLERNAA 204
               ||:.|.|......|.||.|          |.|           ...|.|:..:.|:.||||.
Human    88 ---PSAPAPAPPPPAPAPPTLG----------NNH-----------QESPGWRCCRPTLRERNAL 128

  Fly   205 MFNNELMSDVKFIVGGEFDIDPIQTIPAHKYILATGSSVFYAMFYGGLAENKQEIKVPDVEPTAF 269
            |||||||:||.|:||..   ...:|:|||||:||.|||||||||||.|||.|.||.:|||||.||
Human   129 MFNNELMADVHFVVGPP---GATRTVPAHKYVLAVGSSVFYAMFYGDLAEVKSEIHIPDVEPAAF 190

  Fly   270 LTLLRYLYCDEIKLEPEHILATLYAAKKYIVPHLARACVNYLEVKLTAKNACLLLSQSRLFEEPE 334
            |.||:|:|.|||.||.:.:|||||||||||||.||:||||:||..|.|||||:||||||||||||
Human   191 LILLKYMYSDEIDLEADTVLATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPE 255

  Fly   335 LMQRCWEVIDAQAEMAVKSEDFVDIDLKTFESILSRETLNCKEIHLFEAALNWAMNACEKMSIDD 399
            |.||||||||||||||::||.|.:||.:|.|.|::||.||.||..:|||.||||...|::..:..
Human   256 LTQRCWEVIDAQAEMALRSEGFCEIDRQTLEIIVTREALNTKEAVVFEAVLNWAEAECKRQGLPI 320

  Fly   400 TPQNKRRLLGQALHLIRIPTMSLEEFANGVAQTGILSSQETIDMFLHFTAKMKPSLGFPTRSRAG 464
            ||:|||.:||:||:|:|||||:|||||||.||:.||:.:||..:||.:||..||.|.||...|.|
Human   321 TPRNKRHVLGRALYLVRIPTMTLEEFANGAAQSDILTLEETHSIFLWYTATNKPRLDFPLTKRKG 385

  Fly   465 LKTQVCHRFQSCAYRSNQWRYRGRCDSIQFSVDRRIFIVGFGLYGSSTGAANYNVKIELKRLGRT 529
            |..|.||||||.||||||||||||||||||:||||:||.|.||||||:|.|.|:|||||||||..
Human   386 LAPQRCHRFQSSAYRSNQWRYRGRCDSIQFAVDRRVFIAGLGLYGSSSGKAEYSVKIELKRLGVV 450

  Fly   530 LAENDTKFFSDGSSNTFHVFFENPIQIEPECYYTASVILDGNELSFFGQEGMSEVLMGNVTFQFQ 594
            ||:|.|||.||||||||.|:||:|:|:|.:.:||||.:|||:|||:||||||:||..|.|.||||
Human   451 LAQNLTKFMSDGSSNTFPVWFEHPVQVEQDTFYTASAVLDGSELSYFGQEGMTEVQCGKVAFQFQ 515

  Fly   595 CSSESTNGTGVQGGQIPELIFY 616
            |||:||||||||||||||||||
Human   516 CSSDSTNGTGVQGGQIPELIFY 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lute	NP_001262663.1	BTB_POZ_BTBD3_6	205..315	CDD:349591	75/109 (69%)
		BACK_BTBD3_like	315..409	CDD:350563	60/93 (65%)
		PHR	471..616	CDD:462339	111/144 (77%)
BTBD6	NP_001374496.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..53		7/22 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..115		16/69 (23%)
		BTB_POZ_BTBD6	128..236	CDD:349658	75/110 (68%)
		BACK_BTBD6	236..330	CDD:350600	60/93 (65%)
		PHR	392..537	CDD:462339	111/144 (77%)