DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lute and Btbd17

DIOPT Version :9

Sequence 1:	NP_001262663.1	Gene:	lute / 42089	FlyBaseID:	FBgn0262871	Length:	735	Species:	Drosophila melanogaster
Sequence 2:	XP_017170266.1	Gene:	Btbd17 / 72014	MGIID:	1919264	Length:	485	Species:	Mus musculus

Alignment Length:	346	Identity:	74/346 - (21%)
Similarity:	114/346 - (32%)	Gaps:	107/346 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 IQITQPISAPSSPLASPGALNSSGSSSGGGAGSAGGISGSPTAFCLPSSSAAAAVAAISATPTSG 161
            :..|.|...||:.||              |:...|.:|||  |..||:::..|.|
Mouse     3 LSATVPPVGPSAVLA--------------GSTRPGALSGS--AMSLPAAAQRADV---------- 41

  Fly   162 SGSYVCSAGTNWHFAAVAASNAIDTADPNWQASKATVLERNAAMFNNELMSDVKFIVGGEFDIDP 226
                          ...||..||:.:....|..:..:.:.||        |||...|.. ...|.
Mouse    42 --------------GGEAAGTAINHSHMLLQRLQDLLRQGNA--------SDVILRVQA-VGTDE 83

  Fly   227 IQTIPAHKYILATGSSVFYAMFYGGLAENKQEIKVPDVEPTA--FLTLLRYLYCDEI-----KLE 284
            ::....|:.:|...|.:|..     |..|:.|:.:.:....|  |...:|||||.|:     :..
Mouse    84 VRAFHTHRLLLGLHSELFRE-----LLSNQSEVMLRESRDCAAVFDKFIRYLYCGELTVLLAQAI 143

  Fly   285 PEHILATLYAAKKYIVPHLARACVNYLEVKL----------------TAKNACLLLSQSRLFEEP 333
            |.|.|||     ||.|..|.|...:|:...|                |...|
Mouse   144 PLHRLAT-----KYRVASLQRGVADYMRAHLAGGVGPAVGWYHYAVSTGDEA------------- 190

  Fly   334 ELMQRCWEVIDAQAEMAVKSEDFVDIDLKTFESILSRETLNCK-EIHLFEAALNWAMNACEKMSI 397
             |.:.|.:.:.........|.::..:..:....:|.|..|..: |:.||.|...|...|....::
Mouse   191 -LRESCLQFLAWNLSAVAGSAEWGAVSPELLAQLLQRSDLVLQDELELFHALEAWLGRARPPPTV 254

  Fly   398 DDTPQNKRRLLGQALHLIRIP 418
            .:          :||..||.|
Mouse   255 AE----------RALRAIRYP 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lute	NP_001262663.1	BTB	204..311	CDD:279045	30/113 (27%)
		BTB	213..315	CDD:197585	30/108 (28%)
		BACK	321..427	CDD:197943	17/99 (17%)
		PHR	472..615	CDD:285277
Btbd17	XP_017170266.1	BTB_POZ	67..165	CDD:365784	32/116 (28%)
Btbd17	XP_017170266.1	BACK_BTBD17	173..245	CDD:350568	12/85 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2075
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810