DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lute and BTBD17

DIOPT Version :9

Sequence 1:	NP_001262663.1	Gene:	lute / 42089	FlyBaseID:	FBgn0262871	Length:	735	Species:	Drosophila melanogaster
Sequence 2:	XP_011523093.1	Gene:	BTBD17 / 388419	HGNCID:	33758	Length:	479	Species:	Homo sapiens

Alignment Length:	310	Identity:	68/310 - (21%)
Similarity:	106/310 - (34%)	Gaps:	83/310 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 GSPTAFCLPSSS--AAAAVAAISATPTSGSGSYVCSAGTNWHFAAVAASNAIDTADPNWQASKAT 197
            |:|..||....:  ..|.:|.:.|......|.   :|||:.:.:               ||
Human     7 GAPRLFCREPETFQGEARLALLGAQRADVGGE---AAGTSINHS---------------QA---- 49

  Fly   198 VLERNAAMFNNELMSDVKFIVGGEFDIDPIQTIPAHKYILATGSSVFYAMFYGGLAENKQEIKVP 262
            ||:|...:......|||...|... ..|.::...||:.:|...|.:|..     |..|:.|..:.
Human    50 VLQRLQELLRQGNASDVVLRVQAA-GTDEVRVFHAHRLLLGLHSELFLE-----LLSNQSEAVLQ 108

  Fly   263 DVEPTA--FLTLLRYLYCDEI-----KLEPEHILATLYAAKKYIVPHLARACVNYLEVKL----- 315
            :.:..|  |...:|||||.|:     :..|.|.|||     ||.|..|.|...:|:...|
Human   109 EPQDCAAVFDKFIRYLYCGELTVLLTQAIPLHRLAT-----KYGVSSLQRGVADYMRAHLAGGAG 168

  Fly   316 -----------TAKNACLLLSQSRLFEEPELMQRCWEVIDAQAEMAVKSEDFVDIDLKTFESILS 369
                       |...|              |.:.|.:.:.........|.::..:..:....:|.
Human   169 PAVGWYHYAVGTGDEA--------------LRESCLQFLAWNLSAVAASTEWGAVSPELLWQLLQ 219

  Fly   370 RETLNCK-EIHLFEAALNWAMNACEKMSIDDTPQNKRRLLGQALHLIRIP 418
            |..|..: |:.||.|...|...|....::.:          :||..||.|
Human   220 RSDLVLQDELELFHALEAWLGRARPPPAVAE----------RALRAIRYP 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lute	NP_001262663.1	BTB	204..311	CDD:279045	31/113 (27%)
		BTB	213..315	CDD:197585	31/108 (29%)
		BACK	321..427	CDD:197943	17/99 (17%)
		PHR	472..615	CDD:285277
BTBD17	XP_011523093.1	BTB	54..159	CDD:279045	31/115 (27%)
		BTB	65..163	CDD:197585	31/108 (29%)
		BACK	170..268	CDD:197943	19/114 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2075
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810