DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lute and klhl11

DIOPT Version :9

Sequence 1:	NP_001262663.1	Gene:	lute / 42089	FlyBaseID:	FBgn0262871	Length:	735	Species:	Drosophila melanogaster
Sequence 2:	NP_956077.1	Gene:	klhl11 / 327313	ZFINID:	ZDB-GENE-030131-5524	Length:	679	Species:	Danio rerio

Alignment Length:	196	Identity:	37/196 - (18%)
Similarity:	90/196 - (45%)	Gaps:	19/196 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   232 AHKYILATGSSVFYAMFYGGLAEN-KQEIKVPDVEPTAFL------TLLRYLYCDEIKLEPEHIL 289
            ||:.:||..:..|..:..|..:|: .:.:::.:....|.|      ::::::|..||::...::.
Zfish    79 AHRSVLAAATDYFTPLLGGQFSESVTRRVEMKEWSSEAGLDQETVESVIQFMYTGEIRVSTANVH 143

  Fly   290 ATLYAAKKYIVPHLARACVNYLEVKLTAKNACLLLSQSRLFEEPELMQRCWEVIDAQAEMAVKSE 354
            ..|..|.::::..|...|..:|:.||:..|...:.|.:.::...:|..|..::|.......::.|
Zfish   144 EVLELADRFLLVQLKDFCGEFLKRKLSLGNCVAIHSLAHMYTLDQLALRAVDMIRRNFHKVIQDE 208

  Fly   355 DFVDIDLKTFESILS--RETLNCKEIHLFEAALNWAMNACEKMSIDDTPQNKRRLLGQALHLIRI 417
            :|..:..:.....||  ..|::.:|: ||:|.:.|         :....:.:.:...:...|:|:
Zfish   209 EFYTLPFRLVRDWLSDAEITVDSEEV-LFDAVVKW---------VQKNSEERVKYFEELFRLLRL 263

  Fly   418 P 418
            |
Zfish   264 P 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lute	NP_001262663.1	BTB	204..311	CDD:279045	16/85 (19%)
		BTB	213..315	CDD:197585	17/89 (19%)
		BACK	321..427	CDD:197943	17/100 (17%)
		PHR	472..615	CDD:285277
klhl11	NP_956077.1	BTB	50..166	CDD:279045	16/86 (19%)
		PHA03098	54..541	CDD:222983	37/196 (19%)
		BACK	174..276	CDD:285009	17/101 (17%)
		Kelch_1	369..410	CDD:279660
		KELCH repeat	369..409	CDD:276965
		Kelch_1	412..456	CDD:279660
		KELCH repeat	413..458	CDD:276965
		KELCH repeat	461..511	CDD:276965
		KELCH repeat	572..618	CDD:276965
		Kelch	582..628	CDD:128874
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576644
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840