DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lute and Tango10

DIOPT Version :9

Sequence 1:	NP_001262663.1	Gene:	lute / 42089	FlyBaseID:	FBgn0262871	Length:	735	Species:	Drosophila melanogaster
Sequence 2:	NP_001259461.1	Gene:	Tango10 / 32125	FlyBaseID:	FBgn0030330	Length:	587	Species:	Drosophila melanogaster

Alignment Length:	438	Identity:	107/438 - (24%)
Similarity:	176/438 - (40%)	Gaps:	94/438 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 GGGGASPAGGG----GGPSAAADHNIQITQPISAPSSPLASPGALNSSGSSSGGGAGSAGGISGS 136
            |.|||:|..||    ||...||.                   ||..:.|:..|||.|:.||.:|:
  Fly     5 GNGGAAPVSGGVCGVGGAHGAAG-------------------GADGAGGAGGGGGCGAGGGGAGA 50

  Fly   137 -PTAFCLPSSSAAAAVAAISATPTSGSGSYVCSAGTNWHFAAVAASNAIDTAD------------ 188
             |...  |...||||..|..|...:..|....:...|.:..:.:.:..:::::
  Fly    51 GPGGG--PGGGAAAADLAGEAAGGAAGGDAAINNQANANGTSESPAKGLNSSEDLDAKRRKCRET 113

  Fly   189 PNWQASKATVLERN------AAMFNNELMSDVKFIVGG-EFDIDPIQTIPAHKYILATGSSVFYA 246
            ...|...:|:::.|      |.::..:||||:..:|.| ||        |||:.||...|.||..
  Fly   114 EEGQDEASTMIDANSVLNKIANLYAEQLMSDIVLLVDGKEF--------PAHRVILCASSDVFQV 170

  Fly   247 MF----YGGLAENKQEIKVPDVEPTAFLTLLRYLYCDEIKLEPEHILATLYAAKKYIVPHLARAC 307
            |.    :...:::..|:.........|...::|||..:|::..:.::..|..:.||.:..|...|
  Fly   171 MLMNPEWNECSKHVIELHEEACCSAVFPQFIKYLYVGQIEVTLQTVMPMLALSDKYNIRDLIDLC 235

  Fly   308 VNYLEVKLTAKNAC--LLLS--QSRLFEEP---ELMQRCWEVIDAQAEMAVKSEDFVDIDLKTFE 365
            |:|:. |..||.|.  .|:|  |..|...|   :|.:.....:....||..:|.|||::|.....
  Fly   236 VDYMN-KHVAKAATSGYLVSWLQYTLSFTPTHNDLTETLKRFLKWNLEMVAESRDFVEMDPAILI 299

  Fly   366 SILSRETL-NCKEIHLFEAALNWAMNACEKMS----------IDDTPQNKRRLLG-----QALHL 414
            .:|.:..| ...|..||:....|.::..|:|.          |:.|..:.|  .|     |..||
  Fly   300 LLLQQNDLVVTSEYKLFDILQTWLLHRREQMEATGSGGFMELIEQTVSHIR--FGMMTPRQLSHL 362

  Fly   415 IRIPTMS------LEEFANGVA-QTG----ILSSQETIDMFLHFTAKM 451
            :..|.:.      :|..|.|:: |:|    :...:.|....|.||.::
  Fly   363 LMDPLVEYHKEFLVERIAIGMSYQSGHEDRVREVRATESGKLQFTPRL 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lute	NP_001262663.1	BTB	204..311	CDD:279045	29/111 (26%)
		BTB	213..315	CDD:197585	27/106 (25%)
		BACK	321..427	CDD:197943	30/134 (22%)
		PHR	472..615	CDD:285277
Tango10	NP_001259461.1	BTB	135..239	CDD:279045	29/111 (26%)
		BTB	144..242	CDD:197585	27/106 (25%)
		BACK	258..359	CDD:197943	22/102 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2075
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810