DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lute and Tdpoz8

DIOPT Version :9

Sequence 1:	NP_001262663.1	Gene:	lute / 42089	FlyBaseID:	FBgn0262871	Length:	735	Species:	Drosophila melanogaster
Sequence 2:	NP_001171165.1	Gene:	Tdpoz8 / 229571	MGIID:	3645677	Length:	370	Species:	Mus musculus

Alignment Length:	188	Identity:	43/188 - (22%)
Similarity:	83/188 - (44%)	Gaps:	46/188 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   205 MFNNELMSDVKFIVGG-EFDIDPIQTIPAHKYILATGSSVFYAMFYGGLAENKQEIK------VP 262
            ::.|.|.:|...:|.| ||        .|||.|||..|.||.|||     |::.:::      :.
Mouse   181 LWENSLFTDCCLLVAGHEF--------RAHKVILAARSPVFRAMF-----EHEMKVRLTNRVEIH 232

  Fly   263 DVEPTAFLTLLRYLYCDEIKLEPEHILAT--LYAAKKYIVPHLARACVNYLEVKLTAKNAC--LL 323
            |::|..|..::.::|..:......:.:|:  |.||.:..:..|...|.:.|...|:.:||.  |:
Mouse   233 DLDPQVFKEMMGFIYTGKASHLHSYSMASDVLAAADRCGLKGLKVMCEDALCRNLSVENAAHTLI 297

  Fly   324 LSQSRLFEEPELMQRCWEVIDAQAEMAVKSEDFVDIDLKTFESILSRET--LNCKEIH 379
            |:.....|                .:.:::.||:.:    :.|.:|:.:  ::.:|.|
Mouse   298 LADLHSIE----------------HLKIQALDFITV----YASEVSKTSGWMSMRESH 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lute	NP_001262663.1	BTB	204..311	CDD:279045	30/114 (26%)
		BTB	213..315	CDD:197585	29/110 (26%)
		BACK	321..427	CDD:197943	9/63 (14%)
		PHR	472..615	CDD:285277
Tdpoz8	NP_001171165.1	MATH	16..154	CDD:295307
		BTB	180..284	CDD:279045	30/115 (26%)
		BTB	189..287	CDD:197585	29/110 (26%)
		SPOP_C	287..348	CDD:269807	12/69 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833933
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930