DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lute and Abtb2

DIOPT Version :9

Sequence 1:	NP_001262663.1	Gene:	lute / 42089	FlyBaseID:	FBgn0262871	Length:	735	Species:	Drosophila melanogaster
Sequence 2:	NP_599230.2	Gene:	Abtb2 / 171440	RGDID:	620724	Length:	1024	Species:	Rattus norvegicus

Alignment Length:	139	Identity:	38/139 - (27%)
Similarity:	64/139 - (46%)	Gaps:	13/139 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   207 NNELMSDVKFIVGGEFDIDPIQTIPAHKYILATGSSVFYAMFYGGL---AENKQEIKVPDVEPTA 268
            ||:.||||.|:|.|:.       ..|||.:|.|.|:.|..:.....   .:|.:.|::.|::...
  Rat   839 NNKEMSDVTFLVEGKL-------FYAHKVLLVTASNRFKTLMTNKSEQDGDNSKTIEISDIKYHI 896

  Fly   269 FLTLLRYLY---CDEIKLEPEHILATLYAAKKYIVPHLARACVNYLEVKLTAKNACLLLSQSRLF 330
            |..|::|||   .:.:::....||..|.||..:.:..|.|.|.......|:.::|......:::.
  Rat   897 FQMLMQYLYYGGTESMEIPTADILQLLSAANLFQLDALQRHCEILCSQTLSVESAVNTYKYAKIH 961

  Fly   331 EEPELMQRC 339
            ..|||...|
  Rat   962 NAPELALFC 970

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lute	NP_001262663.1	BTB	204..311	CDD:279045	32/109 (29%)
		BTB	213..315	CDD:197585	28/107 (26%)
		BACK	321..427	CDD:197943	4/19 (21%)
		PHR	472..615	CDD:285277
Abtb2	NP_599230.2	H2A	194..>242	CDD:305064
		Ank_4	<498..542	CDD:290365
		ANK	516..670	CDD:238125
		ANK 1	521..550
		ANK repeat	522..565	CDD:293786
		Ank_2	526..633	CDD:289560
		ANK repeat	567..604	CDD:293786
		ANK 2	567..596
		ANK 3	606..635
		ANK repeat	606..631	CDD:293786
		Ank_2	611..>679	CDD:289560
		ANK 4	649..678
		BTB	836..939	CDD:279045	31/106 (29%)
		BTB	845..946	CDD:197585	28/107 (26%)
		SPOP_C_like	946..>990	CDD:269810	6/25 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337444
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840