DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lute and Spopfm2

DIOPT Version :9

Sequence 1:	NP_001262663.1	Gene:	lute / 42089	FlyBaseID:	FBgn0262871	Length:	735	Species:	Drosophila melanogaster
Sequence 2:	NP_001139579.1	Gene:	Spopfm2 / 100043188	MGIID:	3702972	Length:	357	Species:	Mus musculus

Alignment Length:	209	Identity:	50/209 - (23%)
Similarity:	84/209 - (40%)	Gaps:	39/209 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   205 MFNNELMSD-VKFIVGGEFDIDPIQTIPAHKYILATGSSVFYAMFYGGLAEN-KQEIKVPDVEPT 267
            ::.|.|.:| ..|:.|.||        .|||.|||..|.||.|||...:.|. ...:.:.|::|.
Mouse   181 LWENSLCTDCCLFVAGQEF--------RAHKAILAARSPVFRAMFEHEMVERLTNRVDINDLDPK 237

  Fly   268 AFLTLLRYLYCDEIKLEPEHILA--TLYAAKKYIVPHLARACVNYLEVKLTAKNACLLLSQSRLF 330
            .|..::.::|..:......|.:|  .|.||.:|.:..|...|.:.|...|:.:||...|..:.|.
Mouse   238 VFKEMMGFIYTGKAPHLHIHSMACDLLAAADRYGMEGLMVLCEDALSRNLSVENAAHTLILADLH 302

  Fly   331 EEPELMQRCWEVIDAQAEMAVKSEDFVDIDLKTFESILSRETLNCKEIHLFEAALNWAMNACEKM 395
            ...:|..:..:.|...|....::.:        ::|::....      ||...|.::..:|
Mouse   303 STQQLKTQALDFIALHASKVCETSE--------WKSMVESNP------HLVAEAFHFLASA---- 349

  Fly   396 SIDDTPQNKRRLLG 409
                     ||.||
Mouse   350 ---------RRFLG 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lute	NP_001262663.1	BTB	204..311	CDD:279045	32/109 (29%)
		BTB	213..315	CDD:197585	31/105 (30%)
		BACK	321..427	CDD:197943	14/89 (16%)
		PHR	472..615	CDD:285277
Spopfm2	NP_001139579.1	MATH	16..153	CDD:295307
		BTB	178..283	CDD:279045	32/109 (29%)
		BTB	189..287	CDD:197585	31/105 (30%)
		SPOP_C	287..349	CDD:269807	12/75 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833938
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930