DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lute and btbd11b

DIOPT Version :9

Sequence 1:	NP_001262663.1	Gene:	lute / 42089	FlyBaseID:	FBgn0262871	Length:	735	Species:	Drosophila melanogaster
Sequence 2:	XP_003200483.1	Gene:	btbd11b / 100034519	ZFINID:	ZDB-GENE-050419-99	Length:	1012	Species:	Danio rerio

Alignment Length:	208	Identity:	56/208 - (26%)
Similarity:	90/208 - (43%)	Gaps:	37/208 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   195 KATVLERNAA------MFNNELMSDVKFIVGGEFDIDPIQTIPAHKYILATGSSVFYAMFYGGLA 253
            |.|.::|...      ..||:.||||.|:|.|:    |..   |||.:|.|.|:.|..:.....|
Zfish   808 KLTEIKRKQTSRLDPHFLNNKEMSDVTFLVEGK----PFY---AHKVLLFTASNRFKLLLANRPA 865

  Fly   254 ENKQEIKVPDVEPTAFLTLLRYLYC---DEIKLEPEHILATLYAAKKYIVPHLARACVNYLEVKL 315
            .....|::..|:...|..:::||||   |.:.:....::..|.|:|.:.:..|.|.|    |: :
Zfish   866 AENTCIEISHVKYNVFQLVMQYLYCGGTDALHIRNTEVMDLLSASKFFQLEALQRHC----EI-I 925

  Fly   316 TAKN----ACL-LLSQSRLFEEPELMQRCWEVIDAQAEMAVKSEDFVDIDLKTFESILSRETL-N 374
            .|||    .|: :.:.::..|.|||        .|..|........|.|:|:.|:.:|....: |
Zfish   926 CAKNINTETCVEIYNHAKFLEAPEL--------SAYIEGYFLKNMAVLIELEPFKQLLYNTPVEN 982

  Fly   375 C--KEIHLFEAAL 385
            |  ..:|..|..|
Zfish   983 CCPDVLHDLEKTL 995

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lute	NP_001262663.1	BTB	204..311	CDD:279045	32/115 (28%)
		BTB	213..315	CDD:197585	29/104 (28%)
		BACK	321..427	CDD:197943	17/69 (25%)
		PHR	472..615	CDD:285277
btbd11b	XP_003200483.1	H2A	189..275	CDD:305064
		ANK	506..659	CDD:238125
		ANK repeat	514..555	CDD:293786
		Ank_2	516..622	CDD:289560
		ANK repeat	557..590	CDD:293786
		ANK repeat	592..620	CDD:293786
		ANK repeat	630..668	CDD:293786
		BTB	823..926	CDD:279045	33/114 (29%)
		BTB	832..930	CDD:197585	31/109 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576650
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930