DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lute and abtb2b

DIOPT Version :9

Sequence 1:	NP_001262663.1	Gene:	lute / 42089	FlyBaseID:	FBgn0262871	Length:	735	Species:	Drosophila melanogaster
Sequence 2:	XP_001923186.1	Gene:	abtb2b / 100007078	ZFINID:	ZDB-GENE-100422-14	Length:	1032	Species:	Danio rerio

Alignment Length:	157	Identity:	43/157 - (27%)
Similarity:	71/157 - (45%)	Gaps:	40/157 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   198 VLERNAAM--------FNNELMSDVKFIVGGEFDIDPIQTIPAHKYILATGSSVFYAMFYGGLAE 254
            :.|:.||:        .||:.||||.|:|.|:    |..   ||..:|.|.|..|..:    ||:
Zfish   828 IQEKKAALAAQLDPHFLNNQEMSDVTFLVEGK----PFY---AHGVLLLTASDRFKTL----LAQ 881

  Fly   255 N-------KQEIKVPDVEPTAFLTLLRYLYC---DEIKLEPEHILATLYAAKKYIVPHLARACV- 308
            |       :::|::.:::...|..::.||||   :.:|:....:|..|.||..:.:..|.|.|.
Zfish   882 NGSDSTQTRKDIEISNIKYNIFQMMMSYLYCGGTESLKMGVSELLELLSAASLFQLGVLQRHCEI 946

  Fly   309 ---------NYLEVKLTAK-NACLLLS 325
                     |.:.:..||| |..:.||
Zfish   947 LCAQNIDLDNAVNIYHTAKANGAVELS 973

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lute	NP_001262663.1	BTB	204..311	CDD:279045	35/134 (26%)
		BTB	213..315	CDD:197585	30/121 (25%)
		BACK	321..427	CDD:197943	2/5 (40%)
		PHR	472..615	CDD:285277
abtb2b	XP_001923186.1	Histone	<131..178	CDD:329110
		H2A	181..>235	CDD:330514
		ANK	506..660	CDD:238125
		ANK repeat	514..555	CDD:293786
		ANK repeat	557..594	CDD:293786
		ANK repeat	596..626	CDD:293786
		BTB	842..952	CDD:306997	33/120 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576640
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930