DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Brf and SUA7

DIOPT Version :9

Sequence 1:	NP_001163636.1	Gene:	Brf / 42087	FlyBaseID:	FBgn0038499	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_015411.1	Gene:	SUA7 / 856201	SGDID:	S000006290	Length:	345	Species:	Saccharomyces cerevisiae

Alignment Length:	298	Identity:	64/298 - (21%)
Similarity:	115/298 - (38%)	Gaps:	49/298 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LKCRNCG--SNEIEEDNARGDRVCMNCGSVLEDSLIVSEVQF------EEVGHGAAAIGQFVSAE 61
            |.|..|.  ..:|.|..:.||.||..||.||.|.|:.:..::      :..|...:.:|:..:..
Yeast    22 LTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTRSEWRTFSNDDHNGDDPSRVGEASNPL 86

  Fly    62 SSGGATNYGYGKFQVGSGTESR-EVTIKKA-------KKD---------ITLLCQQLQLSQHYAD 109
            ..|...:...||   |..|:.| ...:.||       |||         ||:||...:|.:...|
Yeast    87 LDGNNLSTRIGK---GETTDMRFTKELNKAQGKNVMDKKDNEVQAAFAKITMLCDAAELPKIVKD 148

  Fly   110 TALNFFKMALGRHLTRGRKSTHIYAACVYMTCRTEGTSHLLIDISDVQQICSYELGRT------- 167
            .|...:|:.......:|:....|.||.:.:.||....:....:|..:..:.:.|.|:|
Yeast   149 CAKEAYKLCHDEKTLKGKSMESIMAASILIGCRRAEVARTFKEIQSLIHVKTKEFGKTLNIMKNI 213

  Fly   168 --------YLKLSHALCINIPSLDPCLYIMRFANRLQLGAKTHEVSMTALRIVQRMKKDCMHSGR 224
                    :||:.   ..|:.......||.||.:.|.|   ..:|:.:|....::.|:....:|:
Yeast   214 LRGKSEDGFLKID---TDNMSGAQNLTYIPRFCSHLGL---PMQVTTSAEYTAKKCKEIKEIAGK 272

  Fly   225 RPTGLCGAALLIAARMHDFSRTMLDVIGVVKIHESTLR 262
            .|..:...::.:...:.....|...|...:::.|.|::
Yeast   273 SPITIAVVSIYLNILLFQIPITAAKVGQTLQVTEGTIK 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Brf	NP_001163636.1	TF_Zn_Ribbon	5..44	CDD:285471	15/40 (38%)
		SUA7	6..270	CDD:224323	63/297 (21%)
		CYCLIN	108..164	CDD:294043	10/55 (18%)
		CYCLIN	183..268	CDD:238003	15/80 (19%)
		BRF1	441..531	CDD:285040
SUA7	NP_015411.1	SUA7	21..333	CDD:224323	64/298 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1405
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810