DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Brf and AT3G09360

DIOPT Version :9

Sequence 1:	NP_001163636.1	Gene:	Brf / 42087	FlyBaseID:	FBgn0038499	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_001326225.1	Gene:	AT3G09360 / 820092	AraportID:	AT3G09360	Length:	604	Species:	Arabidopsis thaliana

Alignment Length:	700	Identity:	195/700 - (27%)
Similarity:	291/700 - (41%)	Gaps:	153/700 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CRNCGSNEIEEDNARGDRVCMNCGSVLEDSLIVSEVQFEEVGHGAAAIGQFVSAESSGGATNYGY 71
            |.:|..|........|...|..||.:||:....:||.|.:     .|.||   :::||....
plant     4 CNHCVKNVPGIRPYDGALACNLCGRILENFHFSTEVTFVK-----NAAGQ---SQASGNIVR--- 57

  Fly    72 GKFQVGSG-TESREVTIKKAKKDITLLCQQLQLSQHYADT---ALNFFKMALGRHLTRGRKSTHI 132
               .|.|| |.|||...:.|:.::..|...|.:.....|.   |..||:||:.::.|:||::..:
plant    58 ---SVQSGITSSRERRFRIARDELMNLKDALGIGDERDDVIVIAAKFFEMAVEQNFTKGRRTELV 119

  Fly   133 YAACVYMTCRTEGTSHLLIDISDVQQICSYELGRTYLKLSHALCI----NIPSL-DPCLYIMRFA 192
            .|:|:|:|||....:.||||.|...::..||||..||:|...|.:    |...| ||.:::.||:
plant   120 QASCLYLTCRELNIALLLIDFSSYLRVSVYELGSVYLQLCEMLYLVENRNYEKLVDPSIFMDRFS 184

  Fly   193 NRLQLGAKTHEVSMTALRIVQRMKKDCMHSGRRPTGLCGAALLIAARMHDFSRTMLDVIGVVKIH 257
            |.|..|....:|..||..|:..||:|.:.:||:|:|:|||||..||..|....:..|::.:|.|.
plant   185 NSLLKGKNNKDVVATARDIIASMKRDWIQTGRKPSGICGAALYTAALSHGIKCSKTDIVNIVHIC 249

  Fly   258 ESTLRKRLSEFAETPSGGLTLEEFMTVDLEREQDPPSFKAARKKDRERIKDMGEHELTELQKEID 322
            |:||.|||.||.:|.||.|.:.|..    |||....||......::|.:..|.:.     .|...
plant   250 EATLTKRLIEFGDTDSGNLNVNELR----ERESHKRSFTMKPTSNKEAVLCMHQD-----SKPFG 305

  Fly   323 AHLEKDLGKYSNSVYRQLTKGKGLSPLSSPSTPNSSSEKDIELEESRQFIEQSNAEVIKELIAKN 387
            ..|.:|..|...:|...|..|.           |..:.:..|.|...:...:.|...|..|   |
plant   306 YGLCEDCYKDFINVSGGLVGGS-----------NPPAFQRAEKERMEKAAREENEGGISSL---N 356

  Fly   388 EDVKKSEPGGLVAGIEGLRPDIEAICRVTQSDLEDVEKAKQPQEQELIT-------DDLNDDELD 445
            .|             |.|..|..::.:..:...|..||.|...|:...|       .|::|||::
plant   357 HD-------------EQLYSDYCSMSKRGKQCSEKGEKDKDGAEEHADTSDESDNFSDISDDEVN 408

  Fly   446 QYVLTEEESVAKLEMWKNLNAEYLQEQKERDERL-----------------------------AK 481
            .|:..|||:..|...|..:|.:||:||..::..|                             ||
plant   409 GYINNEEETHYKTITWTEMNKDYLEEQAAKEAALKAASEALKASNSNCPEDARKAFEAAKADAAK 473

  Fly   482 EREEGKPERKKRKPRKKVIGPSSTAGEAIEKMLQEKKISSKINYEILKTLTDGMGGLTDDSPTTS 546
            .|:|   :::|:....|...|.:||.||:.:.|.:|::||.|||::|::|.|           ||
plant   474 SRKE---KQQKKAEEAKNAAPPATAVEAVRRTLDKKRLSSVINYDVLESLFD-----------TS 524

  Fly   547 ADTKPSTLEELKHQPVIVEEGPVASKSRGNRAAYDLPGPSRKRPKLEVGLPVSKAADVEQAETKP 611
            |                                   |..|.||.|.|..:...|.   |..|.|.
plant   525 A-----------------------------------PEKSPKRSKTETDIEKKKE---ENKEMKS 551

  Fly   612 AVVVEADDLDEDADDPDVEPEAEPEATLQDMLNTGGDDDEFGYGFDEEEE 661
            ......::.|||.:|     |.|......||.....:.::| |..|||||
plant   552 NEHENGENEDEDEED-----EEEGNVESYDMKTDFQNGEKF-YEEDEEEE 595

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Brf	NP_001163636.1	TF_Zn_Ribbon	5..44	CDD:285471	11/36 (31%)
		SUA7	6..270	CDD:224323	94/271 (35%)
		CYCLIN	108..164	CDD:294043	21/58 (36%)
		CYCLIN	183..268	CDD:238003	35/84 (42%)
		BRF1	441..531	CDD:285040	34/118 (29%)
AT3G09360	NP_001326225.1	SUA7	<63..270	CDD:224323	78/206 (38%)
		CYCLIN_TFIIIB90_rpt2	172..263	CDD:410257	38/90 (42%)
		BRF1	400..521	CDD:400202	35/123 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	60	1.000	Domainoid score	I3851
eggNOG	1	0.900	-	-		E1_COG1405
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	192	1.000	Inparanoid score	I1367
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D412601at2759
OrthoFinder	1	1.000	-	-		FOG0002717
OrthoInspector	1	1.000	-	-		otm2628
orthoMCL	1	0.900	-	-		OOG6_101494
Panther	1	1.100	-	-	LDO	PTHR11618
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2091
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.830