DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Brf and AT2G45100

DIOPT Version :9

Sequence 1:	NP_001163636.1	Gene:	Brf / 42087	FlyBaseID:	FBgn0038499	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_001324771.1	Gene:	AT2G45100 / 819117	AraportID:	AT2G45100	Length:	557	Species:	Arabidopsis thaliana

Alignment Length:	682	Identity:	187/682 - (27%)
Similarity:	287/682 - (42%)	Gaps:	163/682 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CRNCGSNEIEEDNARGDR------VCMNCGSVLEDSLIVSEVQFEEVGHGAAAIGQFVSAESSGG 65
            |::||.      |..|.|      .|..||.:||:....:||.|.:     .|.||   :::||.
plant     4 CKHCGK------NVPGIRPYDAALSCDLCGRILENFNFSTEVTFVK-----NAAGQ---SQASGN 54

  Fly    66 ATNYGYGKFQVGSG-TESREVTIKKAKKDITLLCQQLQLSQHYADT---ALNFFKMALGRHLTRG 126
            ...      .|.|| :.|||..|:||..::..|...|.:.....|.   |.|||::||..:.|:|
plant    55 ILK------SVQSGMSSSRERIIRKATDELMNLRDALGIGDDRDDVIVMASNFFRIALDHNFTKG 113

  Fly   127 RKSTHIYAACVYMTCRTEGTSHLLIDISDVQQICSYELGRTYLKLSHALCI----NIPSL-DPCL 186
            |....::::|:|:|||....:.||||.|...::..|:||..||:|...|.|    |...| ||.:
plant   114 RSKELVFSSCLYLTCRQFKLAVLLIDFSSYLRVSVYDLGSVYLQLCDMLYITENHNYEKLVDPSI 178

  Fly   187 YIMRFANRLQLGAKTHEVSMTALRIVQRMKKDCMHSGRRPTGLCGAALLIAARMHDFSRTMLDVI 251
            :|.||:|.|..||..:::.:||..|:..||:|.|.:||:|:|:|||||..||..|....:..|::
plant   179 FIPRFSNMLLKGAHNNKLVLTATHIIASMKRDWMQTGRKPSGICGAALYTAALSHGIKCSKTDIV 243

  Fly   252 GVVKIHESTLRKRLSEFAETPSGGLTLEEFMTVDLEREQDPPSFKAARKKD--RERI-----KDM 309
            .:|.|.|:||.|||.||.:|.:..||.:|....  |||::..:.::.||.:  :|.:     :|.
plant   244 NIVHICEATLTKRLIEFGDTEAASLTADELSKT--EREKETAALRSKRKPNFYKEGVVLCMHQDC 306

  Fly   310 GEHELTELQKEIDAHLEKDLGKYSNSVYRQLTKGKGLSPLSSPSTPNSSSEKDIELEESRQFIEQ 374
                     |.:|..|       ..|.|.:.....|  .|...|.|.:....:.|..|.:...|:
plant   307 ---------KPVDYGL-------CESCYDEFMTVSG--GLEGGSDPPAFQRAEKERMEEKASSEE 353

  Fly   375 SNAEVIKELIAKNEDVKKSEPGGLVAGIEGLRPDIEAICRVTQSDLEDVE---KAKQPQEQELIT 436
            ::.:|       |.|....|..                   |.||::|.|   ..:.|:|..|:
plant   354 NDKQV-------NLDGHSDESS-------------------TLSDVDDRELDCYFRTPEEVRLV- 391

  Fly   437 DDLNDDELDQYVLTEEESVAKLEMWKNL--NAEYLQEQKERDERLAKEREEGKPERKKRKPRKKV 499
            ....|.|...|   :|:..||.....|.  ||..:.|..:  ...||.|:|   :|::|...:|.
plant   392 KIFFDHENPGY---DEKEAAKKAAGLNACNNASNIFEASK--AAAAKSRKE---KRQQRAEEEKN 448

  Fly   500 IGPSSTAGEAIEKMLQEKKISSKINYEILKTLTDGMGGLTDDSPTTSADTKPSTLEELKHQPVIV 564
            ..|.:|..||::.|::.||... ||.:.|:.|.|..                            |
plant   449 APPPATGIEAVDSMVKRKKFRD-INCDYLEELFDAS----------------------------V 484

  Fly   565 EEGPVASKSRGNRAAYDLPGPSRKRPKLEVGLPVSKAADVEQAETKPAVVVEADDLDEDADDPDV 629
            |:.|                   ||.|.|..:...|..:.|        :||.:..:||...|..
plant   485 EKSP-------------------KRSKTETVMEKKKKEEHE--------IVENEQEEEDYAAPYE 522

  Fly   630 EPEAEPEATLQDMLNTGGDDDEFGYGFDEEEE 661
            :.|.:..|..:  :||   |.:|.....||||
plant   523 QDEEDYAAPYE--MNT---DKKFYESEVEEEE 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Brf	NP_001163636.1	TF_Zn_Ribbon	5..44	CDD:285471	13/42 (31%)
		SUA7	6..270	CDD:224323	99/277 (36%)
		CYCLIN	108..164	CDD:294043	21/58 (36%)
		CYCLIN	183..268	CDD:238003	37/84 (44%)
		BRF1	441..531	CDD:285040	27/91 (30%)
AT2G45100	NP_001324771.1	SUA7	<63..259	CDD:224323	75/195 (38%)
		CYCLIN	83..151	CDD:294043	22/67 (33%)
		CYCLIN	180..253	CDD:294043	30/72 (42%)
		BRF1	375..479	CDD:285040	32/113 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	56	1.000	Domainoid score	I4042
eggNOG	1	0.900	-	-		E1_COG1405
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	192	1.000	Inparanoid score	I1367
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D412601at2759
OrthoFinder	1	1.000	-	-		FOG0002717
OrthoInspector	1	1.000	-	-		otm2628
orthoMCL	1	0.900	-	-		OOG6_101494
Panther	1	1.100	-	-	O	PTHR11618
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2091
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.830