| Sequence 1: | NP_001163636.1 | Gene: | Brf / 42087 | FlyBaseID: | FBgn0038499 | Length: | 662 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_060780.2 | Gene: | BRF2 / 55290 | HGNCID: | 17298 | Length: | 419 | Species: | Homo sapiens |
| Alignment Length: | 496 | Identity: | 104/496 - (20%) |
|---|---|---|---|
| Similarity: | 184/496 - (37%) | Gaps: | 151/496 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 6 KCRNCGSNEIEEDN--ARGDRVCMNCGSVLEDSLIVSEVQFEEVGHGAAAIGQFVSAESSGGATN 68
Fly 69 YGYGKFQVGSGTESREVTIKKAK--KDITLLCQQLQLSQHYADTALNFFKMAL---GRHLTRGRK 128
Fly 129 STHIYAACVYMTCR------TEGT--SHLLIDIS---------------DVQQICSYELGRTY-- 168
Fly 169 -LKLSHALCINIPSLDPCLYIMRFANRLQLGAKTHEVSMTALRIVQRMKKDCMHSGRRPTGLCGA 232
Fly 233 ALLIA-ARMHDFSRTMLDVIGVVKIHESTLRKRLSEFAETPSGGLTLEEFMTVDLEREQDPPSFK 296
Fly 297 AARKKDRERIKDMGEHELTELQKEIDAHLEKDLGKYSNSVYRQLTKGKGLSPLSSPSTPNSSSEK 361
Fly 362 DIELE-ESRQFIEQSNAEVIKELIAKNEDVKKSEPGGLVAGI-EGLRPDIEAI----CRVTQSDL 420
Fly 421 EDVEKAKQPQE------QELITDD--LNDDELDQYVLTEEE 453 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Brf | NP_001163636.1 | TF_Zn_Ribbon | 5..44 | CDD:285471 | 12/39 (31%) |
| SUA7 | 6..270 | CDD:224323 | 67/297 (23%) | ||
| CYCLIN | 108..164 | CDD:294043 | 19/81 (23%) | ||
| CYCLIN | 183..268 | CDD:238003 | 16/85 (19%) | ||
| BRF1 | 441..531 | CDD:285040 | 6/13 (46%) | ||
| BRF2 | NP_060780.2 | SUA7 | 5..233 | CDD:224323 | 62/263 (24%) |
| Repetitive region | 72..157 | 21/84 (25%) | |||
| Interaction with target DNA. /evidence=ECO:0000269|PubMed:26638071, ECO:0007744|PDB:4ROC, ECO:0007744|PDB:4ROD, ECO:0007744|PDB:4ROE | 108..114 | 1/5 (20%) | |||
| Repetitive region | 173..249 | 20/90 (22%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 314..351 | 10/46 (22%) | |||
| Required for the formation of a ternary complex with DNA and TBP, not required for interaction with TBP in the absence of DNA. /evidence=ECO:0000269|PubMed:26638071 | 357..363 | 1/5 (20%) | |||
| Required for interaction with TBP and formation of a ternary complex with DNA and TBP. /evidence=ECO:0000269|PubMed:26638071 | 365..419 | 9/34 (26%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG1405 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||