Protein Alignment Det and BIRC5

DIOPT Version :10

• Sequence 1: NP_650608.1
• Gene: Det / 42077
• FlyBaseID: FBgn0264291
• Length: 153
• Species: Drosophila melanogaster
• Sequence 2: NP_001012271.1
• Gene: BIRC5 / 332
• HGNCID: 593
• Length: 165
• Species: Homo sapiens
• Alignment Length: 140
• Identity: 48/140 - (34%)
• Similarity: 66/140 - (47%)
• Gaps: 23/140 - (16%)

  Fly    27 LEQHRVESYKSWPFPETASCSISKMAEAGFYWTGTKRENDTATCFVCGKTLDGWEPEDDP----- 86
            |:.||:.::|:|||.|..:|:..:||||||....|:.|.|.|.||.|.|.|:||||:|||
Human    14 LKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIGPGT 78

  Fly    87 ------------------WKEHVKHAPQCEFAKLSCPERNLTVSQFLEILGTVVKGSIEKTCKAF 133
                              .:||.||:..|.|..:......||:.:||::.....|..|.|.....
Human    79 VAYACNTSTLGGRGGRITREEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNK 143

  Fly   134 KSSFVRENEK 143
            |..|....||
Human   144 KKEFEETAEK 153

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Det	NP_650608.1	BIR	31..101	CDD:459891	35/92 (38%)
BIRC5	NP_001012271.1	BIR	18..110	CDD:459891	34/91 (37%)