DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Det and Birc2

DIOPT Version :9

Sequence 1:	NP_650608.1	Gene:	Det / 42077	FlyBaseID:	FBgn0264291	Length:	153	Species:	Drosophila melanogaster
Sequence 2:	NP_001278432.1	Gene:	Birc2 / 11797	MGIID:	1197009	Length:	612	Species:	Mus musculus

Alignment Length:	85	Identity:	30/85 - (35%)
Similarity:	44/85 - (51%)	Gaps:	6/85 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 EQHRVESYKSWPFPETASCSISKMAEAGFYWTGTKRENDTATCFVCGKTLDGWEPEDDPWKEHVK 92
            |:.|..:|..||.   :..|.:::|.||||:.|   ..|...||.||..|..|||:||...||.:
Mouse   177 EEARFLTYSMWPL---SFLSPAELARAGFYYIG---PGDRVACFACGGKLSNWEPKDDAMSEHRR 235

  Fly    93 HAPQCEFAKLSCPERNLTVS 112
            |.|.|.|.:.:...:..::|
Mouse   236 HFPHCPFLENTSETQRFSIS 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Det	NP_650608.1	BIR	31..101	CDD:279047	28/69 (41%)
Birc2	NP_001278432.1	BIR	45..114	CDD:197595
		BIR 1	46..113
		BIR	176..245	CDD:197595	29/73 (40%)
		BIR 2	177..243		28/71 (39%)
		BIR 3	262..329
		BIR	263..329	CDD:237989
		UBA_BIRC2_3	385..431	CDD:270577
		CARD_BIRC2_BIRC3	447..538	CDD:260038
		RING-HC_BIRC2_3_7	559..612	CDD:319627
		RING-HC finger (C3HC4-type)	565..599	CDD:319627
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R141
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840