DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment m-cup and AT1G03670

DIOPT Version :9

Sequence 1:	NP_650607.1	Gene:	m-cup / 42076	FlyBaseID:	FBgn0038488	Length:	702	Species:	Drosophila melanogaster
Sequence 2:	NP_171863.1	Gene:	AT1G03670 / 839438	AraportID:	AT1G03670	Length:	616	Species:	Arabidopsis thaliana

Alignment Length:	336	Identity:	78/336 - (23%)
Similarity:	128/336 - (38%)	Gaps:	76/336 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 DQDQELNTRQEQEQSVARPSMANERKQSSPKVELTKLSHDLIEECKRSQEDSLLSRHLRHELEKL 87
            |.||....:.:.|..:..|::.. ..::..||.|.|..:|.::..:|
plant    21 DPDQWTIFKDKDESEIMNPAILC-AVRAGDKVSLLKRINDDVKVTQR------------------ 66

  Fly    88 PRDSRRELVRKQRNGCAPLFIACKRGAVDIAEYLITICE---ANIEQRGHFEVPEDNSFHYVSPL 149
                   ||..|.|..  |.||...|.|.|.|::|:...   .|:...|.            :.|
plant    67 -------LVDNQGNSI--LHIAAALGHVHIVEFIISTFPNLLQNVNLMGE------------TTL 110

  Fly   150 WAAVVSGKLSMVKYLVRIGCD-------INATSDSGSTPVRSACYMTHVDIVKFLVENGADIK-R 206
            ..|..:|.|::|:.|||...:       |.|.|.:|.|.:.:|....||::...||....|:. .
plant   111 HVAARAGSLNIVEILVRFITESSSYDAFIAAKSKNGDTALHAALKGKHVEVAFCLVSVKHDVSFD 175

  Fly   207 PNINGGTCLINSVQS--VQLCLYLVRKGA--DINARDIQDKTALHYAIQEHRLDTTKLLIEQGAD 267
            .|.:..:.|..:|::  .:|.|.::...:  .|.|.....|:.:|.|::.:|.|...:::.|  |
plant   176 KNNDEASPLYMAVEAGYHELVLKMLESSSSPSILASMFSGKSVIHAAMKANRRDILGIVLRQ--D 238

  Fly   268 P---YARSRYGDDAL----RTACLKGAHHI---FDFLKKQLHY-------TPARLA--EAHELMG 313
            |   ..|:..|...|    ...|.:|..:|   ||.....|.|       ||..:|  |.|..:.
plant   239 PGLIELRNEEGRTCLSYGASMGCYEGIRYILAEFDKAASSLCYVADDDGFTPIHMAAKEGHVRII 303

  Fly   314 STFLDEHNESR 324
            ..||....:||
plant   304 KEFLKHCPDSR 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
m-cup	NP_650607.1	ANK repeat	101..175	CDD:293786	21/83 (25%)
		Ank_2	<101..174	CDD:289560	20/82 (24%)
		ANK	147..262	CDD:238125	31/126 (25%)
		Ank_2	149..239	CDD:289560	26/101 (26%)
		ANK repeat	177..208	CDD:293786	8/31 (26%)
		ANK repeat	210..239	CDD:293786	6/32 (19%)
		ANK repeat	241..271	CDD:293786	8/32 (25%)
		Ank_4	244..294	CDD:290365	15/59 (25%)
		ANK	591..>657	CDD:238125
		Ank_2	591..>641	CDD:289560
		ANK repeat	611..641	CDD:293786
AT1G03670	NP_171863.1	ANK repeat	40..69	CDD:293786	7/54 (13%)
		ANK repeat	72..103	CDD:293786	10/32 (31%)
		Ank_2	76..172	CDD:372319	28/107 (26%)
		ANK repeat	105..143	CDD:293786	11/49 (22%)
		ANK repeat	145..173	CDD:293786	8/27 (30%)
		ANKYR	<214..364	CDD:223738	27/103 (26%)
		ANK repeat	214..246	CDD:293786	8/33 (24%)
		ANK repeat	248..284	CDD:293786	9/35 (26%)
		ANK repeat	286..318	CDD:293786	9/29 (31%)
		Ank_2	291..376	CDD:372319	7/24 (29%)
		ANK repeat	320..354	CDD:293786
		PGG	443..553	CDD:372845
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2399
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X100
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050