DRSC/TRiP Functional Genomics Resources

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Protein Alignment m-cup and AT4G03450

DIOPT Version :9

Sequence 1:NP_650607.1 Gene:m-cup / 42076 FlyBaseID:FBgn0038488 Length:702 Species:Drosophila melanogaster
Sequence 2:NP_192254.1 Gene:AT4G03450 / 827913 AraportID:AT4G03450 Length:641 Species:Arabidopsis thaliana


Alignment Length:627 Identity:114/627 - (18%)
Similarity:182/627 - (29%) Gaps:284/627 - (45%)


- Green bases have known domain annotations that are detailed below.


  Fly    84 LEKLPRDSRRELV-RKQRNGCAPLFIACKRGAVDIAEYLITICEANIEQRGHFEVPEDNSFHYVS 147
            |:|:..::...|. .:...|...|.:|...|.:::.:.:::.|...:        .|.||...: 
plant    52 LDKMKTNNNTPLACFRNETGDFTLHLAAAWGRLELVKRIVSECPCLL--------LETNSKDQI- 107

  Fly   148 PLWAAVVSGKLSMVKYLVRIGCDINATSDSGSTPVRSACYMTHVDIVKFLVENGADIKRPNINGG 212
            ||.||..:|:|::|:..|   ..:|..||..|                       :.:|..:|  
plant   108 PLHAAAAAGRLAVVEAFV---ARVNEISDGLS-----------------------EEERERVN-- 144

  Fly   213 TCLINSVQSVQLCLYLVRKGADINARDIQDKTALHYAIQEHRLDTTKLLIEQGADPYARSRYGDD 277
                         ||.:        :||...||||.|::...|.|                    
plant   145 -------------LYAM--------KDIDGNTALHLALKGGHLKT-------------------- 168

  Fly   278 ALRTACLKGAHHIFDFLKKQLHYTPARLAEAHELMGSTFLDEHNESRVCILHWRMAHHIRAAYSP 342
               .|||..|:|:..||......:|...|   .:.||..|                         
plant   169 ---AACLVKANHLASFLANNHGVSPLFTA---IIAGSLTL------------------------- 202

  Fly   343 YIEKKPQVPLRTAYENAVEFSTLEELDNIATDMDAMRTQSLLICERVLGLTHKDMLFRLTFRGAS 407
             :|....||.:|.              |:|:.::..:                            
plant   203 -VEAMMYVPGQTC--------------NLASKLEGRK---------------------------- 224

  Fly   408 YADSLQLQRCIDLWRFLLEVRVSNWSILHFETCFAAQALVRLMLDLHVQNSSHIRSDARARFVHQ 472
                                     |::|     ||         |..:||              
plant   225 -------------------------SLVH-----AA---------LKAKNS-------------- 236

  Fly   473 DKVLPRFEDVLGVFRTLSESAIVVKHLLLLRPVFRRQQENYDRVMRCLAHLIYL-----LINTVH 532
                    |:|.|.  |||...:|.         .|.:|.    ..||:...|:     ::|.:|
plant   237 --------DILDVI--LSEDPSLVN---------ERDEEG----RTCLSVAAYVGYYKGVVNLLH 278

  Fly   533 TEAQNKLICQ-----AVHEAVVVGNLR---------------SASTADTMLHLCASRLNVIKSG- 576
            ....|...|.     .:|.||..|.::               .......:||:.|      ||| 
plant   279 RSTSNVFECDDDGSYPIHMAVEKGRVKIFLKLLKCCPDSQYLLNKQGQNILHIAA------KSGK 337

  Fly   577 ---YITDDNFADKTVFPNADVIK--LLIQCGVDVNTKNEAKSTPLHVACQPYNYDNEIVHLLLK- 635
               |:..       |....|:||  |:::..||.|       ||||:|  ...:....|::|.| 
plant   338 TGTYLLQ-------VIKAYDLIKNDLIMEQDVDGN-------TPLHLA--TLTWRPRTVNILNKF 386

  Fly   636 -CGGDIDQPNRADKRPYDLIASNPTSTIPLLNFVTLQCLAAT 676
             .|..:...|:......|:..||..|.......:||..|..|
plant   387 TLGNHLHIRNKDGLSALDIAESNLQSNYVFRERMTLMVLLCT 428

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
m-cupNP_650607.1 ANK repeat 101..175 CDD:293786 17/73 (23%)
Ank_2 <101..174 CDD:289560 17/72 (24%)
ANK 147..262 CDD:238125 25/114 (22%)
Ank_2 149..239 CDD:289560 15/89 (17%)
ANK repeat 177..208 CDD:293786 2/30 (7%)
ANK repeat 210..239 CDD:293786 3/28 (11%)
ANK repeat 241..271 CDD:293786 7/29 (24%)
Ank_4 244..294 CDD:290365 12/49 (24%)
ANK 591..>657 CDD:238125 18/69 (26%)
Ank_2 591..>641 CDD:289560 16/53 (30%)
ANK repeat 611..641 CDD:293786 9/31 (29%)
AT4G03450NP_192254.1 ANK 67..207 CDD:238125 46/249 (18%)
Ank_2 75..176 CDD:289560 35/181 (19%)
ANK repeat 75..102 CDD:293786 5/34 (15%)
ANK repeat 104..150 CDD:293786 16/95 (17%)
ANK 148..311 CDD:238125 54/340 (16%)
Ank_2 <149..207 CDD:289560 22/109 (20%)
ANK repeat 152..184 CDD:293786 14/54 (26%)
Ank_2 228..316 CDD:289560 26/138 (19%)
ANK 251..383 CDD:238125 34/166 (20%)
ANK repeat 256..288 CDD:293786 7/35 (20%)
Ank_2 295..383 CDD:289560 25/109 (23%)
ANK repeat 324..361 CDD:293786 12/49 (24%)
PGG 455..564 CDD:290670
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 77 1.000 Inparanoid score I2399
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X100
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.050

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