DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment m-cup and AT4G03490

DIOPT Version :9

Sequence 1:	NP_650607.1	Gene:	m-cup / 42076	FlyBaseID:	FBgn0038488	Length:	702	Species:	Drosophila melanogaster
Sequence 2:	NP_001328102.1	Gene:	AT4G03490 / 827426	AraportID:	AT4G03490	Length:	710	Species:	Arabidopsis thaliana

Alignment Length:	374	Identity:	82/374 - (21%)
Similarity:	129/374 - (34%)	Gaps:	138/374 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 SLLSRHLRHELEKLPRDSRRELVRKQRNGC--------APLFIACKRGAVDIAEYLITICEANIE 130
            ||...|:...|         :|||:.|:.|        :||::|.:.|.|.:.|:::
plant   151 SLKGNHVSVSL---------QLVREDRSTCFLLDKEDVSPLYMAAEAGYVSLVEHML-------- 198

  Fly   131 QRGHFEVPEDNSFHYVSPLWAAVVSGKLSMVKYLVR----------------------IGCDINA 173
             ||     .|.||...|.|.|||.|..|.::..::.                      ||.||..
plant   199 -RG-----LDASFVGKSVLCAAVKSQNLDILTAVLESDSDLVESRDEDGRTPLATAASIGYDIGV 257

  Fly   174 ----------------TSDSGSTPVRSACYMTHVDIVKFLVENGAD-IKRPNINGGTCLINSVQS 221
                            .::.||.|:.|||.......:|.::::..| |:..|..|...|..:.:|
plant   258 QHMLTRFASSTQVAYIKNEDGSFPIHSACSARCTSALKVILKHHPDTIEMLNSQGQNVLHVAAKS 322

  Fly   222 --VQLCLYLVRKGAD----INARDIQDKTALHYAIQEHRLDTTKLLIEQGADPYARSRYGDDALR 280
              .:...||:|| :|    ||.:||:..|.||.|..........|.|..               |
plant   323 GNARAVGYLLRK-SDVKRLINEQDIEGNTPLHLASSNSHPKVVSLFIHD---------------R 371

  Fly   281 TACLKGAHHIFDFLKKQLHYTPARLAEAHELMGSTFLD---EHNESRVCILHWRMAHHIRAAYSP 342
            ...|           |.|:|           .|.|.||   :|..:...:..|.:...:.||.:
plant   372 RVDL-----------KILNY-----------KGFTALDAAEDHMATIPSLQEWLIWMALVAAGT- 413

  Fly   343 YIEKKPQVPLRTAYENAVEFSTLEELDNIATDMDAM------RTQSLLI 385
              .:.|:|.||.            ::..:.||.|.:      |..:||:
plant   414 --TRAPRVHLRA------------DIPGLTTDEDLILKIHKDRVNTLLV 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
m-cup	NP_650607.1	ANK repeat	101..175	CDD:293786	23/119 (19%)
		Ank_2	<101..174	CDD:289560	23/118 (19%)
		ANK	147..262	CDD:238125	38/159 (24%)
		Ank_2	149..239	CDD:289560	30/134 (22%)
		ANK repeat	177..208	CDD:293786	9/31 (29%)
		ANK repeat	210..239	CDD:293786	10/34 (29%)
		ANK repeat	241..271	CDD:293786	6/29 (21%)
		Ank_4	244..294	CDD:290365	8/49 (16%)
		ANK	591..>657	CDD:238125
		Ank_2	591..>641	CDD:289560
		ANK repeat	611..641	CDD:293786
AT4G03490	NP_001328102.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2399
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X100
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050