DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment m-cup and AT4G14390

DIOPT Version :9

Sequence 1:	NP_650607.1	Gene:	m-cup / 42076	FlyBaseID:	FBgn0038488	Length:	702	Species:	Drosophila melanogaster
Sequence 2:	NP_193175.2	Gene:	AT4G14390 / 827084	AraportID:	AT4G14390	Length:	694	Species:	Arabidopsis thaliana

Alignment Length:	422	Identity:	92/422 - (21%)
Similarity:	153/422 - (36%)	Gaps:	124/422 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 CEANIEQRGHFEVPEDNSFHYVSPLWAAVVSGKLSMVKYLVRIGCD----INATSDSGSTPVRSA 185
            |...:..|| ..|....|....|.|..||..|.|.:||.:|   |:    :...:.||.||:..|
plant   113 CLEKLRSRG-ISVARIKSNTGDSILHLAVTWGHLELVKEIV---CECPRLLLEQNSSGQTPLHVA 173

  Fly   186 CYMTHVDIVKFLVENGADIKRPNINGGTCLINSVQSVQLCLYLVRKGADINARDIQDK---TALH 247
            .:..|..||:..|                .:.:..|.:||   ..:...:|...::||   |||:
plant   174 AHSGHTTIVEAFV----------------ALVTFSSARLC---NEESERMNPYVLKDKDGNTALY 219

  Fly   248 YAIQEHRLDTTKLLIEQGAD-PYARSRYGDDALRTAC-------------------LKGAHHIFD 292
            |||:....:....|:....| |:..::||..:|..|.                   |||.....:
plant   220 YAIEGRYFEMAVCLVNANQDAPFLGNKYGVSSLFVAINTGDVSLVKAILKIIGNKDLKGKKSNLE 284

  Fly   293 FLKKQLHYTPARLAEAHELMG---STFLDEH----NESRV----CILHWRMAHHI---------- 336
             .|.|...:.|.:|...:.:.   ...|||:    :|..:    |:   .:|.||
plant   285 -SKLQGQKSLAHVALVTQSIAGVLDVILDEYPSLMDERDINGWTCL---SLAAHIGYYEGVCNLL 345

  Fly   337 -RAAYSPYI-EKKPQVPLRTA----YENAVE------------FSTL-EELDNIATDMDAMRTQS 382
             |:....|: ::....|:.||    :||.||            .:.| :.:.:||.........:
plant   346 ERSTKGVYVCDQDGSFPIHTAAEKGHENIVEEFIKRCPGSKHLLNKLGQNVLHIAAKNGKFWISN 410

  Fly   383 LLICERVLGLTHKDMLFRLTFRGASYADSLQLQRCIDLWRFLLEVRVSNWSILHFETCFAAQALV 447
            :||       .:||            .:.|.:.:.:| ....|.:.|.||   ||:   :...|.
plant   411 MLI-------INKD------------TEHLGVGQDVD-GNTPLHLAVMNW---HFK---SITWLA 449

  Fly   448 RLMLDLHVQNSSHIRSDARARFVHQDKVLPRF 479
            |....|.|:|    ::..|||.:.:.:|.|.:
plant   450 RSSKILKVRN----KNGLRARDIAEREVKPHY 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
m-cup	NP_650607.1	ANK repeat	101..175	CDD:293786	15/53 (28%)
		Ank_2	<101..174	CDD:289560	15/52 (29%)
		ANK	147..262	CDD:238125	31/121 (26%)
		Ank_2	149..239	CDD:289560	22/93 (24%)
		ANK repeat	177..208	CDD:293786	9/30 (30%)
		ANK repeat	210..239	CDD:293786	4/28 (14%)
		ANK repeat	241..271	CDD:293786	11/33 (33%)
		Ank_4	244..294	CDD:290365	16/69 (23%)
		ANK	591..>657	CDD:238125
		Ank_2	591..>641	CDD:289560
		ANK repeat	611..641	CDD:293786
AT4G14390	NP_193175.2	ANK	127..268	CDD:238125	39/162 (24%)
		Ank_2	136..239	CDD:289560	31/124 (25%)
		ANK repeat	165..211	CDD:293786	13/64 (20%)
		ANK repeat	213..238	CDD:293786	7/24 (29%)
		ANKYR	291..505	CDD:223738	44/220 (20%)
		ANK	319..448	CDD:238125	29/157 (18%)
		ANK repeat	324..356	CDD:293786	6/34 (18%)
		ANK repeat	358..390	CDD:293786	7/31 (23%)
		ANK repeat	392..426	CDD:293786	8/52 (15%)
		PGG	513..620	CDD:290670
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2399
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X100
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050