Protein Alignment CG5265 and YAT2

DIOPT Version :10

• Sequence 1: NP_650605.1
• Gene: CG5265 / 42074
• FlyBaseID: FBgn0038486
• Length: 643
• Species: Drosophila melanogaster
• Sequence 2: NP_010941.1
• Gene: YAT2 / 856745
• SGDID: S000000826
• Length: 923
• Species: Saccharomyces cerevisiae
• Alignment Length: 789
• Identity: 157/789 - (19%)
• Similarity: 258/789 - (32%)
• Gaps: 218/789 - (27%)

  Fly    34 SYSTAKDKPKSDQPNLLKYHVLPLEEILNRFMITVQPL----------LTPEEFKKQEKITNEFQ 88
            ::...::.||...|.|.        :.|.|...:::||          |.||:.:|...|..:|:
Yeast    16 TFKHEEELPKLPLPKLC--------DTLQRLKESLEPLYYADGYYQHPLDPEQIEKLSSIIRDFE 72

  Fly    89 -----RKEGAKLQK-------LLEETGEQEKNWLAHRWLKVAYLQFRSPVTCFSS---PGMTFPK 138
                 .|..:|||.       .|:|......|..:.|.::...|. |:|....:.   |.:|...
Yeast    73 ENPVSEKLQSKLQSYHDTRDCYLDELHLDINNQTSTREIQDDVLP-RNPFLVLADDALPNITQAD 136

  Fly   139 QKFESVHEF---------------VDYTSRVIFGLGEFNDLVHAKKIPIVKMGKNELDNSQFGKV 188
            :....||..               ::.|:.....:..|.:|....:.|:.:.|  |::|....|.
Yeast   137 RSAVLVHSAARFISALKQDLLPPDINATNGKPLSMAPFLNLFGTTRSPVFQRG--EVENFDLNKP 199

  Fly   189 FGTCRI-----------------------PRRFTDDIV--------YNPCSDYVVVIYRNHFYQL 222
            :....:                       .|:..:||.        .:|.|.::::|.|..:|.|
Yeast   200 YTASDLEDPDYSSDEDDNDEPTQKDFDDRKRKHEEDIFTGNGITIKRHPDSKHILIISRGQYYTL 264

  Fly   223 KIYDKEGKLIIAPCLAVQLEEIMAKEK---EPGVPYGILTTDSRDNWAEAYEHLSNTPRNRVALK 284
            ::.|...|:|........:...:.|:.   |.....|.||:.|..||..|.:.|.....|.  |.
Yeast   265 EVLDSTNKIIYTAAELTTIFNHIIKDSSGIEKSTALGSLTSHSFRNWKYARKRLQKRYPNE--LH 327

  Fly   285 TIQNAMFTVSLDEC--TSPKEG---RDAEELILTLIHGKGSKCNSAN------------------ 326
            .|.:|:|.:.|||.  .:..:|   .|..::....|..:..||.|||
Yeast   328 RIDSALFVLVLDESQEETTNDGDDTADISQMFNRTITERDKKCTSANCKRVFYGTSIINSKGHQV 392

  Fly   327 -----RWMDKTIQLVVNPNGHVGFTYEHSPAEGQ------------------------------- 355
                 ||.|| :||||..:......::....:|.
Yeast   393 GSCVSRWYDK-LQLVVTADAKATVIWDSFTCDGSVVLRFTSEIYTESVLRLARDVNAGDPQFSLW 456

  Fly   356 PIAMMMDYVVKKMKDDPSYGECGSENFIPAKKIKFCDVSKCVEQWLIIAQKNVDKLVQDLQMKVL 420
            |....||...||:.......:.|..:.|..|.:    |:|....:..|...:|......|...:.
Yeast   457 PNVTQMDPETKKLMTATISADGGGPSEIDPKLV----VNKIDWSFSNILNTHVHLSETKLADLIS 517

  Fly   421 KFDC------YGKDFIKKQRLG--PDSFVQMALQLAFFKLHYEPAAQYESAHLRIFDGGRTETIR 477
            |:|.      .|:.  ..||||  |||.||:|||:|.:.|:.......|....|.|...|:..|.
Yeast   518 KYDIVRASIPLGRR--SAQRLGVKPDSMVQVALQIAHYALYGRMVFGLEPVSTRGFKNSRSSFIN 580

  Fly   478 SCSNESLAFCHAMDDVSASAQERASKIREAVMCHQMYAKLALLGKGVDRHL------------FG 530
            ..|...|..|......|....::..|..:....|....|.|..|.|.::|.            ||
Yeast   581 IQSQALLELCQLFISSSIDGTDKLDKFIQTCETHNNMVKHAKSGVGYEKHFNALKYLFKFHDHFG 645

  Fly   531 LKLMA---------VENCLPVPEFFSSPGYVKSTHFRMSTSQVATKYDAFMGYGPSVEDGYACCY 586
            :.|..         .||.|.:|  ||.|..:.:.....:|:.        .|..|:|..|:...|
Yeast   646 IHLSGDESSAAKDLFENPLVLP--FSQPELIVANCGNAATTT--------FGITPAVPHGFGIGY 700

  Fly   587 NPREHDIILAI----------------------SAWRHCQATDHQKIAKALAQSFAEMKDVLETC 629
            ..::..:.|.:                      |.||..:.|.|.|....:    :.:.|.|...
Yeast   701 IIKDDQVDLTVTSQFRQGDRLMFMLSWVLGEIRSYWRMSRGTSHNKTGVKI----SPVVDKLYEM 761

  Fly   630 PASKDKPPE 638
            ..:.:.||:
Yeast   762 DNAVNNPPK 770

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5265	NP_650605.1	Carn_acyltransf	54..617	CDD:459926	149/746 (20%)
YAT2	NP_010941.1	Carn_acyltransf	26..725	CDD:459926	145/728 (20%)