DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5265 and crata

DIOPT Version :9

Sequence 1:	NP_650605.1	Gene:	CG5265 / 42074	FlyBaseID:	FBgn0038486	Length:	643	Species:	Drosophila melanogaster
Sequence 2:	NP_001005587.1	Gene:	crata / 449545	ZFINID:	ZDB-GENE-040927-17	Length:	631	Species:	Danio rerio

Alignment Length:	610	Identity:	218/610 - (35%)
Similarity:	353/610 - (57%)	Gaps:	38/610 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 QPNLLKYHVLPLEEILNRFMITVQPLLTPEEFKKQEKITNEFQRKEGA--KLQKLLEETGEQEKN 108
            |..|.|..|.||::..:|::..:.|::.|||.....|:..:||:..|.  :|||.||....:..|
Zfish    37 QEGLPKLPVPPLKQTCDRYLAALDPIVDPEELNHTRKLLEDFQKPGGVGERLQKGLESRAAKLNN 101

  Fly   109 WLAHRWLKVAYLQFRSPVTCFSSPGMTFPKQKFESVHEFVDYTSRVIFGLGEFNDLVHAKKIPIV 173
            ||:..||:.|||.:|.||...||||:..|:.:|......:.|.:::|.|:.:|..::..:.:|:.
Zfish   102 WLSDWWLQTAYLDYRMPVVVHSSPGVVLPRMEFSDRQGQMRYAAKLIAGVLDFKSMIDNETLPLE 166

  Fly   174 KMGKNELDNSQFGKVFGTCRIPRRFTDDIV-----YNPCSDYVVVIYRNHFYQLKIYDKEGKLII 233
            .:|...|...|:.:|..:||||....|.:|     ..| |.::.|::...|:.|.:|:.:|..:.
Zfish   167 YLGGKPLCMHQYYQVLSSCRIPGTKRDTVVNYAMDKRP-STHITVVHNFQFFVLDVYNSDGTPLT 230

  Fly   234 APCLAVQLEEI----MAKEKEPGVPYGILTTDSRDNWAEAYEHLSNTPRNRVALKTIQNAMFTVS 294
            ...:.:|||:|    :...||   |.||||::.|::|.:||.:|.....|:.:::.||.::|||.
Zfish   231 VDQIYIQLEKIWNSSLQTNKE---PIGILTSNHRNSWGKAYNNLIKDKTNKESVRAIQKSIFTVC 292

  Fly   295 LDECTSPKEGRDAEELILT-----LIHGKGSKCNSANRWMDKTIQLVVNPNGHVGFTYEHSPAEG 354
            ||   :|.. |.::::..|     ::||.||:.||.|||.|||:|.::..:|..|..|||:||||
Zfish   293 LD---APMP-RASDDMYRTRAGVQMLHGGGSRWNSGNRWFDKTLQFIIGEDGTCGLIYEHAPAEG 353

  Fly   355 QPIAMMMDYVVKKMKDDPSYGECGSENFIPAK---KIKF---CDVSKCVEQWLIIAQKNVDKLVQ 413
            .||..::|:||:.||.    .|......:|.:   |::|   .::.|.:|.    |::|::.:|.
Zfish   354 PPIVSILDHVVEYMKK----SEMVRTPMVPLRMPQKLRFNITPEIKKDIED----AKQNMNIMVH 410

  Fly   414 DLQMKVLKFDCYGKDFIKKQRLGPDSFVQMALQLAFFKLHYEPAAQYESAHLRIFDGGRTETIRS 478
            ||.::|..|..:||:|.|.|::.||:|:|||||||:::::......||||.||:|..|||:||||
Zfish   411 DLDLRVNVFTHFGKNFPKSQKMSPDAFIQMALQLAYYRIYKRCCPTYESASLRMFRLGRTDTIRS 475

  Fly   479 CSNESLAFCHAMDDVSASAQERASKIREAVMCHQMYAKLALLGKGVDRHLFGLKLMAVENCLPVP 543
            .|::|.:|..||||......|:.:.:.:||..|:.|..:|:.|:.:||||.||||.|:|:...:|
Zfish   476 ASSDSASFVKAMDDPVKHNTEKVALLDKAVKAHRSYTDMAIRGQAIDRHLLGLKLQAIEDLAALP 540

  Fly   544 EFFSSPGYVKSTHFRMSTSQVATKYDAFMGYGPSVEDGYACCYNPREHDIILAISAWRHCQATDH 608
            |.|....|..:.|:.:|||||..|.|..|.:||.|.|||..||||.:..|..|:||:..||.|:.
Zfish   541 EIFMDTSYAVALHYNLSTSQVPAKTDCVMCFGPVVPDGYGVCYNPMDTHINFAVSAFNSCQDTNA 605

  Fly   609 QKIAKALAQSFAEMKDVLETCPASK 633
            .::|:.|..:..:|:.:||..|.:|
Zfish   606 VRLAQGLEDALLDMRTLLEQTPRAK 630

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5265	NP_650605.1	Carn_acyltransf	49..623	CDD:279140	212/595 (36%)
crata	NP_001005587.1	Carn_acyltransf	40..620	CDD:279140	212/595 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594973
Domainoid	1	1.000	403	1.000	Domainoid score	I686
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H598
Inparanoid	1	1.050	414	1.000	Inparanoid score	I1807
OMA	1	1.010	-	-		QHG59015
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	1	1.000	-	-		FOG0001049
OrthoInspector	1	1.000	-	-		otm24513
orthoMCL	1	0.900	-	-		OOG6_102174
Panther	1	1.100	-	-	O	PTHR22589
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X630
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910