DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5265 and cratb

DIOPT Version :9

Sequence 1:	NP_650605.1	Gene:	CG5265 / 42074	FlyBaseID:	FBgn0038486	Length:	643	Species:	Drosophila melanogaster
Sequence 2:	NP_001004594.2	Gene:	cratb / 447855	ZFINID:	ZDB-GENE-040912-162	Length:	614	Species:	Danio rerio

Alignment Length:	599	Identity:	210/599 - (35%)
Similarity:	342/599 - (57%)	Gaps:	44/599 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 VLPLEEILNRFMITVQPLLTPEEFKKQEKITNEF--QRKEGAKLQKLLEETGEQEKNWLAHRWLK 116
            |.||.:.|.|::..::|||..:|.:...:|..||  ....|..||:.|.:..:...||::..|::
Zfish    32 VPPLGQTLQRYLAALEPLLPEDELEHTRRIVQEFGCAGGLGESLQRELIKRAKHSHNWISDWWVQ 96

  Fly   117 VAYLQFRSPVTCFSSPGMTFPKQKFESVHEFVDYTSRVIFGLGEFNDLVHAKKIPIVKMGKNELD 181
            .|||:.|.|:...|:|.::.||:.|......:.:.|::|.|:..|...|.:.::.|..|..|.|.
Zfish    97 WAYLECRQPLAVHSNPAISLPKRDFTDWRGQLVFASKLIAGVLNFKAEVDSGRLAIEYMRGNPLC 161

  Fly   182 NSQFGKVFGTCRIPRRFTDDIVY------NPCSDYVVVIYRNHFYQLKIYDKEGKLIIAPCLAVQ 240
            ...|.|:|.:||||....|.:|:      .|.  ::.|:....|:||.:|:.:|..:....:..|
Zfish   162 MELFPKLFSSCRIPGPKHDLVVHYGRPRRGPA--HITVVRNYQFFQLDVYNSDGTPLTESQIHAQ 224

  Fly   241 LEEIMAK----EKEPGVPYGILTTDSRDNWAEAYEHLSNTPRNRVALKTIQNAMFTVSLDECTSP 301
            |..|.::    :||   |.||||::.|..|.:||..|.....|:.:::.|:.::||:.||   ||
Zfish   225 LLRIRSQSWKTDKE---PMGILTSEHRHTWGQAYTRLLRDKINKESVRLIEKSLFTLCLD---SP 283

  Fly   302 ----KEGRDAEELILTLIHGKGSKCNSANRWMDKTIQLVVNPNGHVGFTYEHSPAEGQPIAMMMD 362
                .:...:..:...::||.|:..||.|||.|||:|.||..:|..|..|||:.|||.|||.::|
Zfish   284 VMRISDENYSSRMAAQILHGGGTYSNSGNRWFDKTLQFVVGEDGSWGLLYEHATAEGPPIATLLD 348

  Fly   363 YVVK--KMKDD---PSYGECGSENFIP---AKKIKFCDVSKCVEQW-LIIAQKNVDKLVQDLQMK 418
            :|::  ||.|.   |         .||   .||:.|...|:.  :| |.:|::|:|.|:.||.:|
Zfish   349 HVLEYCKMTDSVRAP---------LIPLPMPKKLYFYINSEI--KWDLEMAKQNLDILINDLDIK 402

  Fly   419 VLKFDCYGKDFIKKQRLGPDSFVQMALQLAFFKLHYEPAAQYESAHLRIFDGGRTETIRSCSNES 483
            ...|.|:||.|:|:.:|.|:||||:|:|||::::|.|..|..:.|.||:|.||||:.|||.:|:.
Zfish   403 CFNFQCFGKKFVKQLKLSPNSFVQLAIQLAYYRVHNEVCAACDIASLRMFRGGRTDYIRSPTNQM 467

  Fly   484 LAFCHAMDDVSASAQERASKIREAVMCHQMYAKLALLGKGVDRHLFGLKLMAVENCLPVPEFFSS 548
            |:|..|.|||:.|.:.:...:||||..:.:..:.:|:|:|:||||.||||.|:||.|.||..|..
Zfish   468 LSFIQAFDDVAVSREAKIQLLREAVNAYSLLTEQSLMGQGIDRHLLGLKLQAIENGLSVPRIFMD 532

  Fly   549 PGYVKSTHFRMSTSQVATKYDAFMGYGPSVEDGYACCYNPREHDIILAISAWRHCQATDHQKIAK 613
            ..|..:||:::.|.||.|..|:.|.:||.|.||||.||||::..:..:::|:..|:.|:.:|:|.
Zfish   533 TAYGLATHWKLRTGQVPTNTDSVMCFGPLVPDGYAVCYNPQQDHLHFSVTAFNCCEDTNAEKLAL 597

  Fly   614 ALAQSFAEMKDVLE 627
            .|.:|..:::::.:
Zfish   598 TLERSLRDVQELFQ 611

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5265	NP_650605.1	Carn_acyltransf	49..623	CDD:279140	210/593 (35%)
cratb	NP_001004594.2	Carn_acyltransf	28..607	CDD:279140	210/593 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594971
Domainoid	1	1.000	403	1.000	Domainoid score	I686
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	414	1.000	Inparanoid score	I1807
OMA	1	1.010	-	-		QHG59015
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	1	1.000	-	-		FOG0001049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102174
Panther	1	1.100	-	-	O	PTHR22589
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X630
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.910