DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5265 and CROT

DIOPT Version :9

Sequence 1:	NP_650605.1	Gene:	CG5265 / 42074	FlyBaseID:	FBgn0038486	Length:	643	Species:	Drosophila melanogaster
Sequence 2:	NP_001334704.1	Gene:	CROT / 43332	FlyBaseID:	FBgn0039543	Length:	618	Species:	Drosophila melanogaster

Alignment Length:	623	Identity:	169/623 - (27%)
Similarity:	279/623 - (44%)	Gaps:	50/623 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 YSTAKDKPKSDQPNLLKYHVLP-LEEILNRFMITVQPLLTPEEFKKQEKITNEFQRKEGAKLQKL 98
            :.:..||...|....|....|| |.:.:.|:...:||..|.||..:..|..:|||...||:|.:.
  Fly     8 FMSKDDKNTFDFDETLPSLPLPELRDTMERYYSCIQPFGTKEELAQARKTIDEFQNGVGAQLHEQ 72

  Fly    99 LEETGEQEKNWLAHRWLKVAYLQFRSPVTCFSSPGMTFPKQ-KFESVHEFVDY----TSRVIFGL 158
            |::.....:|||...|....|...|.|:..:..  |..|.| :...|.|..:|    .:|.|...
  Fly    73 LKKRAAGMRNWLGTWWEDYGYHLIRMPLLPYQL--MVMPSQLEMVGVPETPEYMLKSLARHIHHS 135

  Fly   159 GEFNDLVHAKKIPIVKM--GKNELDNSQFGKVFGTCRIPRRFTDDIVYN-------PCSDYVVVI 214
            .||.||.....|..:..  ||.:..::.:...|.|||:|....|.|..:       ....::::.
  Fly   136 LEFWDLTRKSSIKPLSSNGGKIKYSSALYKHFFSTCRVPGEEQDHIEKHFLTKDEGKTPSHMLIS 200

  Fly   215 YRNHFYQLKIYDKEGKLIIAPCLAVQLEEIMA-KEKEP-GVPYGILTTDSRDNWAEAYEHLSNTP 277
            .:...:......::..::.||.:.|.|:.:.: .:.|| |.....|:.|.|..||
  Fly   201 GKGRQFIFDCVHEDDTILSAPEILVALQRVRSILDYEPLGDCVPTLSHDERSTWA---------- 255

  Fly   278 RNRVALKTIQNA-------MFTVSLDECTSPKEGRDAEELILTLIHGKGSKCNSANRWMDKTIQL 335
            |||..|:.|..|       :.:..::.|...:..:|.||.....::|     :..:||.|::..:
  Fly   256 RNRNRLREISVANKETLLLVESACMEICWYEQSPKDYEESCQLGLYG-----DLHSRWADRSSSI 315

  Fly   336 VVNPNGHVGFTYEHSPAEGQPIAMMMDYVVKKMKD--DPSYGECGSENFIPAKKIKFCDVSKCVE 398
            :...||...:|.|||..:|........::.....:  :|.:.|....|.:..|::.| .:...::
  Fly   316 IAFRNGRCNWTGEHSCYDGTVSISYATFMQLSFLEVPEPDWAEAEKGNVLEVKELHF-QLDDTLK 379

  Fly   399 QWLIIAQKNVDKLVQDLQMKVLKFDCYGKDFIKKQRLGPDSFVQMALQLAFFKLHYEPAAQYESA 463
            ..:...||::|....|:.:....||.|||||:|..||.||||||:.:|.|::::|.|.|..||:|
  Fly   380 NEIKRVQKDIDDRGIDVTVTFTAFDDYGKDFMKTHRLHPDSFVQVVMQWAYYQMHKEIAPTYETA 444

  Fly   464 HLRIFDGGRTETIRSCSNESLAFCHAMDDVSASAQERASKIREAVMCHQMYAKLALLGKGVDRHL 528
            .:|.:..|||||:|||::....|..|..:........|...|.||..|:.:...|..|.|:||||
  Fly   445 LMRQYYNGRTETLRSCTSAVAEFLRASSNKQVGDMSLARAFRRAVDEHKHFMNEARKGHGIDRHL 509

  Fly   529 FGLKLMAVENCLPVPEFFSSPGYVKS---THFRMSTSQVATKYDAFMGY-GPSVEDGYACCYNPR 589
            |||...|.|:.:.:|.|:..|.|.||   .:|.:|:|.:.  :.|.:|: .|.|.|||...|:..
  Fly   510 FGLWCAAYESKMDIPAFYDDPMYTKSGGGGNFVLSSSTLG--FTANVGFVAPMVFDGYGVFYSIT 572

  Fly   590 EHDIILAISAWRHCQATDHQKIAKALAQSFAEMKDVLE 627
            ...:.:..:|:|....|..:|.......||..:..:||
  Fly   573 SEAVFINTTAYRDSLKTSARKFNDIFKDSFRRISVLLE 610

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5265	NP_650605.1	Carn_acyltransf	49..623	CDD:279140	164/603 (27%)
CROT	NP_001334704.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469040
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22589
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950