DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5265 and CRAT

DIOPT Version :9

Sequence 1:	NP_650605.1	Gene:	CG5265 / 42074	FlyBaseID:	FBgn0038486	Length:	643	Species:	Drosophila melanogaster
Sequence 2:	NP_001287195.1	Gene:	CRAT / 40787	FlyBaseID:	FBgn0037440	Length:	662	Species:	Drosophila melanogaster

Alignment Length:	643	Identity:	475/643 - (73%)
Similarity:	537/643 - (83%)	Gaps:	7/643 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFRDNGKVLWNFARISALQQTRYTFGKK-MPIASYSTAKDKPKSDQPNLLKYHVLPLEEILNRF 64
            ||||.|||:|||..:.|..||:.....|| :|.:||||.:.....:||||||||||||||.||||
  Fly    25 MKFRGNGKLLWNLTKNSLAQQSPNGIAKKVLPASSYSTVQKTIPLEQPNLLKYHVLPLEETLNRF 89

  Fly    65 MITVQPLLTPEEFKKQEKITNEFQRKEGAKLQKLLEETGEQEKNWLAHRWLKVAYLQFRSPVTCF 129
            |.||:||||||||::|:.||:||.:|:|.:||.||||||.:|||||||||||.|||.:|.|||.|
  Fly    90 MTTVEPLLTPEEFQRQKGITSEFLKKQGRELQLLLEETGSKEKNWLAHRWLKAAYLTYRDPVTVF 154

  Fly   130 SSPGMTFPKQKFESVHEFVDYTSRVIFGLGEFNDLVHAKKIPIVKMGKNELDNSQFGKVFGTCRI 194
            .|||||||||.|.....|||||:|||:|||||||:|||.||||||||||||||||||||||||||
  Fly   155 VSPGMTFPKQNFRDSRAFVDYTARVIYGLGEFNDMVHANKIPIVKMGKNELDNSQFGKVFGTCRI 219

  Fly   195 PRRFTDDIVYNPCSDYVVVIYRNHFYQLKIYDKEGKLIIAPCLAVQLEEIMAKEKEPGVPYGILT 259
            |||.||:|||||.||||||||:|||||||||.||||||.|||||.|||.|:.||.:.||||||||
  Fly   220 PRRGTDEIVYNPDSDYVVVIYKNHFYQLKIYSKEGKLIAAPCLAAQLENIVLKETQVGVPYGILT 284

  Fly   260 TDSRDNWAEAYEHLSNTPRNRVALKTIQNAMFTVSLDECTSPKEGRDAEELILTLIHGKGSKCNS 324
            ||||||||||||:|..||.||.||||||.|:|||||||.|..|||.:.:||||:||||.|||.||
  Fly   285 TDSRDNWAEAYEYLVETPGNRDALKTIQGALFTVSLDEGTILKEGEETDELILSLIHGSGSKINS 349

  Fly   325 ANRWMDKTIQLVVNPNGHVGFTYEHSPAEGQPIAMMMDYVVKKMKDDPSYGECGSENFIPAKKIK 389
            .||||||||||||||||:|||||||||||||||||||||||:|||:|||:|:.||::|.||:||:
  Fly   350 GNRWMDKTIQLVVNPNGNVGFTYEHSPAEGQPIAMMMDYVVQKMKEDPSFGQSGSQDFAPAQKIQ 414

  Fly   390 FCDVSKCVEQWLIIAQKNVDKLVQDLQMKVLKFDCYGKDFIKKQRLGPDSFVQMALQLAFFKLHY 454
            |...:|.:|:.|.:||:|||||...||||||||:.:||||||||||||||||||||||||:|:|.
  Fly   415 FSSSNKSLEKSLNVAQENVDKLADALQMKVLKFNGFGKDFIKKQRLGPDSFVQMALQLAFYKMHS 479

  Fly   455 EPAAQYESAHLRIFDGGRTETIRSCSNESLAFCHAMDDVSASAQERASKIREAVMCHQMYAKLAL 519
            ||.|||||||||||||||||||||||||||||..||.|.:.:.||||:|:||||:.||.||||||
  Fly   480 EPPAQYESAHLRIFDGGRTETIRSCSNESLAFSRAMQDPNVTDQERAAKLREAVVSHQTYAKLAL 544

  Fly   520 LGKGVDRHLFGLKLMAVENCLPVPEFFSSPGYVKSTHFRMSTSQVATKYDAFMGYGPSVEDGYAC 584
            .||||||||.||||||:|:..|:||||.|||:|||:|||||||||||||||||||||:.:|||||
  Fly   545 QGKGVDRHLLGLKLMALEHSKPIPEFFKSPGFVKSSHFRMSTSQVATKYDAFMGYGPATDDGYAC 609

  Fly   585 CYNPREHDIILAISAWRHCQATDHQKIAKALAQSFAEMKDVLETCPASKDKPPELKCK 642
            |||||::||||||||||||..|||.|..|.|.|||.|||:|||      ..|||.|.|
  Fly   610 CYNPRDNDIILAISAWRHCPITDHLKFVKTLEQSFFEMKNVLE------KNPPETKSK 661

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5265	NP_650605.1	Carn_acyltransf	49..623	CDD:279140	442/573 (77%)
CRAT	NP_001287195.1	Carn_acyltransf	74..648	CDD:279140	442/573 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469032
Domainoid	1	1.000	403	1.000	Domainoid score	I686
eggNOG	1	0.900	-	-		E1_KOG3717
Homologene	1	1.000	-	-		H598
Inparanoid	1	1.050	414	1.000	Inparanoid score	I1807
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59015
OrthoDB	1	1.010	-	-		D15298at7147
OrthoFinder	1	1.000	-	-		FOG0001049
OrthoInspector	1	1.000	-	-		otm24513
orthoMCL	1	0.900	-	-		OOG6_102174
Panther	1	1.100	-	-	P	PTHR22589
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X630
	13	12.810