DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5265 and CG5122

DIOPT Version :9

Sequence 1:	NP_650605.1	Gene:	CG5265 / 42074	FlyBaseID:	FBgn0038486	Length:	643	Species:	Drosophila melanogaster
Sequence 2:	NP_609601.1	Gene:	CG5122 / 34703	FlyBaseID:	FBgn0032471	Length:	1263	Species:	Drosophila melanogaster

Alignment Length:	619	Identity:	283/619 - (45%)
Similarity:	410/619 - (66%)	Gaps:	10/619 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 KMPIASYSTAKDKPKSDQPNLLKYHVLPLEEILNRFMITVQPLLTPEEFKKQEKITNEFQRKEGA 93
            |..|...:.|.:.| :.:|.|.|:..|||::.:..::.:::|.|..||.|.::|:..:|...|||
  Fly   646 KSEIRHLADANNDP-NKKPELKKFPALPLKQSIASYLSSIEPFLNEEELKVEQKVAKKFVDNEGA 709

  Fly    94 KLQKLLEETGEQEKNWLAHRWLKVAYLQFRSPVTCFSSPGMTFPKQKFESVHEFVDYTSRVIFGL 158
            |||:||||..|...|||..||.:.|||.:::|:|.|||||::||.|:|:..::|:::|::.|:|:
  Fly   710 KLQQLLEEEAEGTDNWLTPRWTRSAYLTYQAPLTVFSSPGLSFPIQEFKDTNDFLNFTAKAIYGM 774

  Fly   159 GEFNDLVHAKKIPIVKMGKNELDNSQFGKVFGTCRIPRRFTDDIVYNPCSDYVVVIYRNHFYQLK 223
            .||..||...|||:|:|||::||||||||:|||.|.|.||.|.|.....:||:||:|.|::::|.
  Fly   775 CEFKQLVDQNKIPVVQMGKHQLDNSQFGKIFGTVRKPGRFCDTIEQYNDADYIVVVYNNNYFKLP 839

  Fly   224 IYDKEGKLIIAPCLAVQLEEIMAKEKEPGVPYGILTTDSRDNWAEAYEHLSNTPRNRVALKTIQN 288
            ||.:.|.|:.|..|...|::|:....:.|..:|:||.|:|.||||||..|.....|...::||:.
  Fly   840 IYSQSGALLHAHTLRDALQDILECPIKVGKHFGLLTHDNRSNWAEAYTVLCRPHGNADTVETIEQ 904

  Fly   289 AMFTVSLDECTSPKEGRDAEELIL---TLIHGKGSKCNSANRWMDKTIQLVVNPNGHVGFTYEHS 350
            ::|.|.||.|....:|   ||.|:   .|:||.|.:.|||||||||||||:|||||..||.||||
  Fly   905 SLFVVCLDNCVPTPKG---EERIVQAHQLLHGGGVRQNSANRWMDKTIQLIVNPNGLAGFCYEHS 966

  Fly   351 PAEGQPIAMMMDYVVKKMKDDPSYG--ECGSENFIPAKKIKFCDVSKCVEQWLIIAQKNVDKLVQ 413
            ||:.||:||:||:|..|: .:|:||  .|.::..:.:..:||..|::|:..||..|::|:.::|.
  Fly   967 PADCQPLAMLMDFVQLKV-TEPNYGCEGCEADKKVTSNLLKFQPVNECINLWLCQARRNIQRIVS 1030

  Fly   414 DLQMKVLKFDCYGKDFIKKQRLGPDSFVQMALQLAFFKLHYEPAAQYESAHLRIFDGGRTETIRS 478
            .|||.|:.|:||||.|||.|.|.|||::||||.||::.::.:..|||||||||||..||||||||
  Fly  1031 QLQMNVINFECYGKCFIKAQGLNPDSYIQMALSLAYYSMYGKIPAQYESAHLRIFHEGRTETIRS 1095

  Fly   479 CSNESLAFCHAMDDVSASAQERASKIREAVMCHQMYAKLALLGKGVDRHLFGLKLMAVENCLPVP 543
            .||||..|..||....||..|:.:.:::||..|:...|.|:.|:|:|||||||:.||:|..:|:|
  Fly  1096 TSNESKTFLLAMQSEKASMSEKLAALQKAVDAHEKLIKEAINGQGIDRHLFGLQEMALEKGMPIP 1160

  Fly   544 EFFSSPGYVKSTHFRMSTSQVATKYDAFMGYGPSVEDGYACCYNPREHDIILAISAWRHCQATDH 608
            |||.|.|||:|..|::.||||||..:.||.|||.:.|||..||||:|..|..|||||:.|:..:.
  Fly  1161 EFFRSKGYVRSVTFQLFTSQVATSNEGFMAYGPLLSDGYGVCYNPKESKITFAISAWKSCKEINT 1225

  Fly   609 QKIAKALAQSFAEMKDVLETCPASKDKPPELKCK 642
            .:.|||:.:|..:|:.::......:......||:
  Fly  1226 IRFAKAIKKSLNDMRKLILLTGGERAGEHPCKCE 1259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5265	NP_650605.1	Carn_acyltransf	49..623	CDD:279140	275/578 (48%)
CG5122	NP_609601.1	Carn_acyltransf	665..1240	CDD:279140	275/578 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469033
Domainoid	1	1.000	403	1.000	Domainoid score	I686
eggNOG	1	0.900	-	-		E1_KOG3717
Homologene	1	1.000	-	-		H598
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D15298at7147
OrthoFinder	1	1.000	-	-		FOG0001049
OrthoInspector	1	1.000	-	-		otm24513
orthoMCL	1	0.900	-	-		OOG6_102174
Panther	1	1.100	-	-	P	PTHR22589
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X630
	11	10.750