DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5265 and Cpt1b

DIOPT Version :9

Sequence 1:	NP_650605.1	Gene:	CG5265 / 42074	FlyBaseID:	FBgn0038486	Length:	643	Species:	Drosophila melanogaster
Sequence 2:	XP_006242242.1	Gene:	Cpt1b / 25756	RGDID:	2397	Length:	775	Species:	Rattus norvegicus

Alignment Length:	588	Identity:	177/588 - (30%)
Similarity:	284/588 - (48%)	Gaps:	76/588 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 SDQPNLLKYHVLPLEEILNRFMITVQPLLTPEEFKKQEKITNEFQRKEGAKLQKLLEETGEQEKN 108
            |.|.:|.|..|..:...::|::.:|:|||..|.:.:.|.:..|||.|...:|||.|........|
  Rat   168 SFQTSLPKLPVPSVPATIHRYLDSVRPLLDDEAYFRMESLAKEFQDKIAPRLQKYLVLKSWWATN 232

  Fly   109 WLAHRWLKVAYLQFRSPVTCFSS-PGMTFPKQKFESVHEFVDYTSRVIFGLGEFNDLVHA----- 167
            :::..|.:..||:.|||:...|: ..|.|         ..:..||:....||   :.|||
  Rat   233 YVSDWWEEYVYLRGRSPIMVNSNYYAMDF---------VLIKNTSQQAARLG---NTVHAMIMYR 285

  Fly   168 KKI------PIVKMGKNELDNSQFGKVFGTCRIPRRFTDDIVYNPCSDYVVVIYRNHFYQLKIYD 226
            :|:      |::.:|...:.:.|..::|.|.|||.:.||.:.:...|.:|.|.::..|:::.:|
  Rat   286 RKLDREEIKPVMALGMVPMCSYQMERMFNTTRIPGKETDLLQHLSESRHVAVYHKGRFFKVWLY- 349

  Fly   227 KEGKLIIAP-CLAVQLEEIM--AKEKEPG-VPYGILTTDSRDNWAEAYEHLSNTPRNRVALKTIQ 287
             ||..::.| .|.:|.:.|:  ....:|| .....||...|..||||.:...::.:|:::|.||:
  Rat   350 -EGSCLLKPRDLEMQFQRILDDTSPPQPGEEKLAALTAGGRVEWAEARQKFFSSGKNKMSLDTIE 413

  Fly   288 NAMFTVSLDE---CTSPKEGRDAEELILTLIHGKGSKCNSANRWMDKTIQLVVNPNGHVGFTYEH 349
            .|.|.|:|||   |.:|.:.........:|:||     |..|||.||:..|:...||.:|...||
  Rat   414 RAAFFVALDEDSHCYNPDDEASLSLYGKSLLHG-----NCYNRWFDKSFTLISCKNGQLGLNTEH 473

  Fly   350 SPAEGQPIAMMMDYVVKKMKDDPSYGECG------SENFIPAKKIKFCDVSKC---VEQWLIIAQ 405
            |.|:...|..:.::|:........|.|.|      :....|.:::::....:|   :|....:|:
  Rat   474 SWADAPIIGHLWEFVLATDTFHLGYTETGHCVGEPNTKLPPPQRMQWDIPEQCQTAIENSYQVAK 538

  Fly   406 KNVDKLVQDLQMKVLKFDCYGKDFIKKQRLGPDSFVQMALQLAFFKLHYEPAAQYESAHLRIFDG 470
                .|..|:::...:|..:||..|||.|..||:|||:|||||.|:...:....||::..|:|..
  Rat   539 ----ALADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDKGKFCLTYEASMTRMFRE 599

  Fly   471 GRTETIRSCSNESLAFCHAMDDVSASAQERASKIREAVMCHQMYAKLALLGKGVDRHLFGL---- 531
            |||||:|||::||.||..||...|...|:.....|:|...||...:||:.|.|:|||||.|
  Rat   600 GRTETVRSCTSESTAFVRAMMTGSHKKQDLQDLFRKASEKHQNMYRLAMTGAGIDRHLFCLYIVS 664

  Fly   532 KLMAVENCLPVPEFFSSPGYVKSTHFRMSTSQV----ATKYD---------AFMGYGPSVEDGYA 583
            |.:.|.:.. :.|..|.|       :.:||||:    ...:|         |..|:||..:.||.
  Rat   665 KYLGVRSPF-LDEVLSEP-------WSLSTSQIPQFQICMFDPKQYPNHLGAGGGFGPVADHGYG 721

  Fly   584 CCY 586
            ..|
  Rat   722 VSY 724

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5265	NP_650605.1	Carn_acyltransf	49..623	CDD:279140	175/583 (30%)
Cpt1b	XP_006242242.1	CPT_N	1..47	CDD:406797
Cpt1b	XP_006242242.1	Carn_acyltransf	173..764	CDD:395612	175/583 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559299at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920