Protein Alignment CG5265 and CPT1B

DIOPT Version :10

• Sequence 1: NP_650605.1
• Gene: CG5265 / 42074
• FlyBaseID: FBgn0038486
• Length: 643
• Species: Drosophila melanogaster
• Sequence 2: NP_004368.1
• Gene: CPT1B / 1375
• HGNCID: 2329
• Length: 772
• Species: Homo sapiens
• Alignment Length: 671
• Identity: 197/671 - (29%)
• Similarity: 314/671 - (46%)
• Gaps: 89/671 - (13%)

  Fly     3 FRDNGKVLWNFARISALQQTRYTFGKKMPIASYSTAKDKPKSDQPNLLKYHVLPLEEILNRFMIT 67
            |..:||.. |..||.|           |.|...|:......|.|.:|.|..|..:...:.|::.:
Human   139 FEMHGKTS-NLTRIWA-----------MCIRLLSSRHPMLYSFQTSLPKLPVPRVSATIQRYLES 191

  Fly    68 VQPLLTPEEFKKQEKITNEFQRKEGAKLQKLLEETGEQEKNWLAHRWLKVAYLQFRSPVTCFSSP 132
            |:|||..||:.:.|.:..|||.|...:|||.|........|:::..|.:..||:.|||:...|:
Human   192 VRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVLKSWWASNYVSDWWEEYIYLRGRSPLMVNSN- 255

  Fly   133 GMTFPKQKFESVHEFVDYT--SRVIFGLGEFNDLVHA-----KKI------PIVKMGKNELDNSQ 184
                        :..:|..  ...........:::||     :|:      |::.:|...:.:.|
Human   256 ------------YYVMDLVLIKNTDVQAARLGNIIHAMIMYRRKLDREEIKPVMALGIVPMCSYQ 308

  Fly   185 FGKVFGTCRIPRRFTDDIVYNPCSDYVVVIYRNHFYQLKIYDKEGKLIIAP-CLAVQLEEIMAKE 248
            ..::|.|.|||.:.||.:.:...|.:|.|.::..|::|.:|  ||..::.| .|.:|.:.|:
Human   309 MERMFNTTRIPGKDTDVLQHLSDSRHVAVYHKGRFFKLWLY--EGARLLKPQDLEMQFQRIL--- 368

  Fly   249 KEPGVP------YGILTTDSRDNWAEAYEHLSNTPRNRVALKTIQNAMFTVSLDECTSPKEGRDA 307
            .:|..|      ...||...|..||:|.:...::.:|:.||:.|:.|.|.|:|||.:...:..|.
Human   369 DDPSPPQPGEEKLAALTAGGRVEWAQARQAFFSSGKNKAALEAIERAAFFVALDEESYSYDPEDE 433

  Fly   308 EELIL---TLIHGKGSKCNSANRWMDKTIQLVVNPNGHVGFTYEHSPAEGQPIAMMMDYVVKKMK 369
            ..|.|   .|:||     |..|||.||:..|:...||.:|...||:.|:...|..:.::|:....
Human   434 ASLSLYGKALLHG-----NCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEFVLGTDS 493

  Fly   370 DDPSY---GEC-GSEN--FIPAKKIKFCDVSKCVEQWLIIAQKNVDK-LVQDLQMKVLKFDCYGK 427
            ....|   |.| |..|  ..|..::::....:|  |.:|.:...|.| |..|:::...:|..:||
Human   494 FHLGYTETGHCLGKPNPALAPPTRLQWDIPKQC--QAVIESSYQVAKALADDVELYCFQFLPFGK 556

  Fly   428 DFIKKQRLGPDSFVQMALQLAFFKLHYEPAAQYESAHLRIFDGGRTETIRSCSNESLAFCHAMDD 492
            ..|||.|..||:|||:|||||.|:...:....||::..|:|..|||||:|||::||.||..||.:
Human   557 GLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVQAMME 621

  Fly   493 VSASAQERASKIREAVMCHQMYAKLALLGKGVDRHLFGLKLMAVENCLPVPEFFSSP--GYVKST 555
            .|.:..:.....::|...||...:||:.|.|:|||||.|.|  |...|.|    |||  ..|.|.
Human   622 GSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCLYL--VSKYLGV----SSPFLAEVLSE 680

  Fly   556 HFRMSTSQVATK----YD---------AFMGYGPSVEDGYACCYN-PREHDIILAISAWRHCQAT 606
            .:|:||||:...    :|         |..|:||..:|||...|. ..|:.|...||:......|
Human   681 PWRLSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGYGVSYMIAGENTIFFHISSKFSSSET 745

  Fly   607 DHQKIAKALAQSFAEMKDVLE 627
            :.|:....:.::..::.|:.:
Human   746 NAQRFGNHIRKALLDIADLFQ 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5265	NP_650605.1	Carn_acyltransf	54..617	CDD:459926	182/608 (30%)
CPT1B	NP_004368.1	CPT_N	1..47	CDD:465132
		Carn_acyltransf	176..756	CDD:459926	182/610 (30%)