Protein Alignment CG5255 and PRSS27

DIOPT Version :10

• Sequence 1: NP_650604.1
• Gene: CG5255 / 42073
• FlyBaseID: FBgn0038485
• Length: 273
• Species: Drosophila melanogaster
• Sequence 2: NP_114154.1
• Gene: PRSS27 / 83886
• HGNCID: 15475
• Length: 290
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 88/272 - (32%)
• Similarity: 136/272 - (50%)
• Gaps: 32/272 - (11%)

  Fly     2 LLILLPLVLFTSSAASQILYPPQYTKNRIVGGEEAAAGLAPYQISLQGIGSGAHSCGGAIIDERW 66
            ||:||......:.||:....|...  ||:|||::...|..|:|:|:|  .:|:|.|||::|.|:|
Human     9 LLLLLCFGSQRAKAATACGRPRML--NRMVGGQDTQEGEWPWQVSIQ--RNGSHFCGGSLIAEQW 69

  Fly    67 IITAAHCTRGRQATA-FRVLTGTQDLHQNGSKYYYPD-RIVEHSN--YAPRKYRNDIALLHLNES 127
            ::|||||.|....|: ::||.|.:.|.|.|....|.. |.|| ||  |.......|:||:.|...
Human    70 VLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVE-SNPLYQGTASSADVALVELEAP 133

  Fly   128 IVFDNATQPVELDHEALV--PGSRLLLTGWGTLSLGGDV---PARLQSLEVNYVPFEQCRAAHDN 187
            :.|.|...||.|...:::  .|....:||||:.| ..|:   |..||.|.|..:...:|...:..
Human   134 VPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPS-EEDLLPEPRILQKLAVPIIDTPKCNLLYSK 197

  Fly   188 STRVDIGH---------VCT-FNDKGRGACHGDSGGPLV----HNGKLVALVNWGLPCAK-GYPD 237
            .|  :.|:         :|. |.:..:.||.||||||||    .:.....:::||..||: ..|.
Human   198 DT--EFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPG 260

  Fly   238 AHASISYYHDFI 249
            .:..::.:|::|
Human   261 VYIRVTAHHNWI 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5255	NP_650604.1	Tryp_SPc	29..249	CDD:214473	79/243 (33%)
PRSS27	NP_114154.1	Tryp_SPc	36..275	CDD:238113	79/243 (33%)