Protein Alignment CG5255 and TPSB2

DIOPT Version :10

• Sequence 1: NP_650604.1
• Gene: CG5255 / 42073
• FlyBaseID: FBgn0038485
• Length: 273
• Species: Drosophila melanogaster
• Sequence 2: NP_077078.5
• Gene: TPSB2 / 64499
• HGNCID: 14120
• Length: 275
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 88/287 - (30%)
• Similarity: 130/287 - (45%)
• Gaps: 53/287 - (18%)

  Fly     1 MLLILLPLV---LFTSSAASQILYPPQYTKNRIVGGEEAAAGLAPYQISLQGIGS-GAHSCGGAI 61
            :||:.||::   .:.:.|..|.|     .:..||||:||.....|:|:||:.... ..|.|||::
Human     4 LLLLALPVLASRAYAAPAPGQAL-----QRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSL 63

  Fly    62 IDERWIITAAHCTRG--RQATAFRVLTGTQDLHQNGSKYYYPD------RIVEHSNYAPRKYRND 118
            |..:|::|||||...  :...|.||....|.|       ||.|      ||:.|..:...:...|
Human    64 IHPQWVLTAAHCVGPDVKDLAALRVQLREQHL-------YYQDQLLPVSRIIVHPQFYTAQIGAD 121

  Fly   119 IALLHLNESIVFDNATQPVELD--HEALVPGSRLLLTGWGTLSLGGDV--------PARLQSLEV 173
            ||||.|.|.:...:....|.|.  .|...||....:|||      |||        |..|:.::|
Human   122 IALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGW------GDVDNDERLPPPFPLKQVKV 180

  Fly   174 NYVPFEQCRAAH-------DNSTRVDIGHVCTFNDKGRGACHGDSGGPLV--HNGKLV--ALVNW 227
            ..:....|.|.:       |:...|....:|..|.: |.:|.||||||||  .||..:  .:|:|
Human   181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSW 244

  Fly   228 GLPCAK-GYPDAHASISYYHDFIRTHL 253
            |..||: ..|..:..::||.|:|..::
Human   245 GEGCAQPNRPGIYTRVTYYLDWIHHYV 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5255	NP_650604.1	Tryp_SPc	29..249	CDD:214473	80/250 (32%)
TPSB2	NP_077078.5	Tryp_SPc	31..268	CDD:238113	80/250 (32%)