DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG5255 and AZU1

DIOPT Version :9

Sequence 1:NP_650604.1 Gene:CG5255 / 42073 FlyBaseID:FBgn0038485 Length:273 Species:Drosophila melanogaster
Sequence 2:NP_001691.1 Gene:AZU1 / 566 HGNCID:913 Length:251 Species:Homo sapiens


Alignment Length:255 Identity:77/255 - (30%)
Similarity:123/255 - (48%) Gaps:28/255 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 LLILLPLVLFTSSAASQILYPPQYTKNRIVGGEEAAAGLAPYQISLQGIGSGAHSCGGAIIDERW 66
            :|.||..:|.:|.|.|..|..       ||||.:|.....|:..|:|  ..|.|.||||:|..|:
Human     6 VLALLAGLLASSRAGSSPLLD-------IVGGRKARPRQFPFLASIQ--NQGRHFCGGALIHARF 61

  Fly    67 IITAAHCTRGRQATAFRVLTGTQDL--HQNGSKYYYPDRIVEHSNYAPRKYRNDIALLHLN-ESI 128
            ::|||.|.:.:......|:.|..||  .:..|:..:....:..:.|.|::..||:.||.|: |:.
Human    62 VMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREAN 126

  Fly   129 VFDNAT-QPVELDHEALVPGSRLLLTGWGTLSLGGDVPARLQSLEVNYVPFEQCRAAHDNSTRVD 192
            :..:.| .|:.|.:..:..|:|..:.|||:...||.:....:.:.|...|.:|||.         
Human   127 LTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP--------- 182

  Fly   193 IGHVCT--FNDKGRGACHGDSGGPLVHNGKLVALVNWGL-PCAKGYPDAHASISYYHDFI 249
             .:|||  ...:| |.|:||.|.|||..|....:.::.| ||.:| ||....::.:.|:|
Human   183 -NNVCTGVLTRRG-GICNGDGGTPLVCEGLAHGVASFSLGPCGRG-PDFFTRVALFRDWI 239

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5255NP_650604.1 Tryp_SPc 29..249 CDD:214473 68/226 (30%)
Tryp_SPc 30..252 CDD:238113 69/227 (30%)
AZU1NP_001691.1 Tryp_SPc 27..240 CDD:238113 69/227 (30%)
Possesses antibiotic activity. /evidence=ECO:0000269|PubMed:8506327 46..70 12/23 (52%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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