Protein Alignment CG5255 and PRSS8

DIOPT Version :10

• Sequence 1: NP_650604.1
• Gene: CG5255 / 42073
• FlyBaseID: FBgn0038485
• Length: 273
• Species: Drosophila melanogaster
• Sequence 2: NP_002764.1
• Gene: PRSS8 / 5652
• HGNCID: 9491
• Length: 343
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 83/272 - (30%)
• Similarity: 128/272 - (47%)
• Gaps: 23/272 - (8%)

  Fly     4 ILLPLVLFTSSAASQILYPP--QYTKNRIVGGEEAAAGLAPYQISLQGIGSGAHSCGGAIIDERW 66
            |||.|.|..|...::....|  ...:.||.||..|.||..|:|:|:  ...|.|.|||:::.|:|
Human    17 ILLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSI--TYEGVHVCGGSLVSEQW 79

  Fly    67 IITAAHC-TRGRQATAFRVLTGTQ--DLHQNGSKYYYPDRIVEHSNYAPRKYRNDIALLHLNESI 128
            :::|||| .......|:.|..|..  |.:...:|......|:.|.:|.....:.|||||.|:..|
Human    80 VLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPI 144

  Fly   129 VFDNATQPVELD--HEALVPGSRLLLTGWGTL--SLGGDVPARLQSLEVNYVPFEQCRAAHDNST 189
            .|....:|:.|.  :.:...|....:||||.:  |:....|..||.|||..:..|.|...::...
Human   145 TFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDA 209

  Fly   190 RVDIGH------VCT-FNDKGRGACHGDSGGPLVHNGK----LVALVNWGLPC-AKGYPDAHASI 242
            :.:..|      ||. :.:.|:.||.|||||||....:    |..:|:||..| |:..|..:...
Human   210 KPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLA 274

  Fly   243 SYYHDFIRTHLS 254
            |.|..:|::.::
Human   275 SSYASWIQSKVT 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5255	NP_650604.1	Tryp_SPc	29..249	CDD:214473	75/238 (32%)
PRSS8	NP_002764.1	Tryp_SPc	45..284	CDD:238113	75/240 (31%)