DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5255 and PRSS2

DIOPT Version :9

Sequence 1:NP_650604.1 Gene:CG5255 / 42073 FlyBaseID:FBgn0038485 Length:273 Species:Drosophila melanogaster
Sequence 2:NP_001290343.1 Gene:PRSS2 / 5645 HGNCID:9483 Length:261 Species:Homo sapiens


Alignment Length:261 Identity:81/261 - (31%)
Similarity:130/261 - (49%) Gaps:24/261 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 LLPLVLFTSSAASQILYPPQYTKNRIVGGEEAAAGLAPYQISLQGIGSGAHSCGGAIIDERWIIT 69
            ||.::.|.::|.:    .|....::||||........|||:||   .||.|.|||::|.|:|:::
Human     3 LLLILTFVAAAVA----APFDDDDKIVGGYICEENSVPYQVSL---NSGYHFCGGSLISEQWVVS 60

  Fly    70 AAHC----------TRGRQATAFRVLTGTQDLH--QNGSKYYYPDRIVEHSNYAPRKYRNDIALL 122
            |.||          .||.:....:|..|..::.  :...::....:|:.|..|..|...|||.|:
Human    61 AGHCYKSAINSKLSGRGCEYHRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLI 125

  Fly   123 HLNESIVFDNATQPVELDHEALVPGSRLLLTGWG-TLSLGGDVPARLQSLEVNYVPFEQCRAAHD 186
            .|:...|.::....:.|.......|:..|::||| |||.|.|.|..||.|:...:...:|.|::.
Human   126 KLSSPAVINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYP 190

  Fly   187 NSTRVDIGHVCT-FNDKGRGACHGDSGGPLVHNGKLVALVNWGLPCA-KGYPDAHASISYYHDFI 249
            .  ::.....|. |.:.|:.:|.||||||:|.||:|..:|:||..|| |..|..:..:..|.|:|
Human   191 G--KITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWI 253

  Fly   250 R 250
            :
Human   254 K 254

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5255NP_650604.1 Tryp_SPc 29..249 CDD:214473 75/234 (32%)
Tryp_SPc 30..252 CDD:238113 76/236 (32%)
PRSS2NP_001290343.1 Tryp_SPc 23..253 CDD:214473 75/234 (32%)
Tryp_SPc 24..256 CDD:238113 76/236 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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