Protein Alignment CG5255 and KLK15

DIOPT Version :10

• Sequence 1: NP_650604.1
• Gene: CG5255 / 42073
• FlyBaseID: FBgn0038485
• Length: 273
• Species: Drosophila melanogaster
• Sequence 2: NP_059979.2
• Gene: KLK15 / 55554
• HGNCID: 20453
• Length: 256
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 77/268 - (28%)
• Similarity: 124/268 - (46%)
• Gaps: 41/268 - (15%)

  Fly     4 ILLPLVLFTSSAASQILYPPQYTKNRIVGGEEAAAGLAPYQISLQGIGSGAHSCGGAIIDERWII 68
            :||.|....:|.|:|       ..::::.|:|.|....|:|::|  ...|..:||.::|...|::
Human     3 LLLTLSFLLASTAAQ-------DGDKLLEGDECAPHSQPWQVAL--YERGRFNCGASLISPHWVL 58

  Fly    69 TAAHCTRGRQATAFRVLTGTQDLHQNGSKYYYPD------RIVEHSNYAPRKYRNDIALLHLNES 127
            :||||    |:...||..|..:|.:...    |:      |::.|..|..|.:||||.||.|.:.
Human    59 SAAHC----QSRFMRVRLGEHNLRKRDG----PEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQP 115

  Fly   128 IVFDNATQPVELDHEALVPGSRLLLTGWGTLS------LGG-----DVPARLQSLEVNYVPFEQC 181
            ...:...:|..|......||...:::|||.:|      .|.     .:|..|....::.:....|
Human   116 ARLNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSC 180

  Fly   182 RAAHDNSTRVDIGHVCTFNDKGRGA--CHGDSGGPLVHNGKLVALVNWG-LPCAK-GYPDAHASI 242
            ..::..  |:....||. ..:||||  |.||||||||..|.|..:|:|| :||.. ..|..:..:
Human   181 DKSYPG--RLTNTMVCA-GAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKV 242

  Fly   243 SYYHDFIR 250
            .:|.::||
Human   243 CHYLEWIR 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5255	NP_650604.1	Tryp_SPc	29..249	CDD:214473	69/240 (29%)
KLK15	NP_059979.2	Tryp_SPc	25..249	CDD:214473	69/236 (29%)